Imbalanced expression of neuronal differentiation marker doublecortin in miR-451a<sup>-/-</sup> mice.
- Christa Trattnig (6000572)
- Muammer Üçal (6000575)
- Carmen Tam-Amersdorfer (6000578)
- Angela Bucko (6000581)
- Ulrike Zefferer (3815314)
- Gerda Grünbacher (6000584)
- Markus Absenger-Novak (6000587)
- Kristin Anna Öhlinger (6000590)
- Klaus Kraitsy (567246)
- Daniel Hamberger (6000593)
- Ute Schaefer (375802)
- Silke Patz (567252)
Publication date
November 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
Neuronal differentiation in the subgranular zone (SGZ) of dentate gyrus (DG) in hippocampus was evaluated by doublecortin (DCX) immunostaining of coronal brain sections of wild type and miR-451a-/- animals. Qualitative evaluation revealed markedly lower expression of DCX in the miR-451a-/- group at postnatal days 30 (A, B) and 50 (C, D). Immunostainings were conducted with at least two coronal sections per animal with n≥4 animals per group per time point. Scale bars: 50 μm.</p
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