Alternative promoters/exons of the mouse <i>Mest</i> locus.

Joomyeong Kim (40689)
Bambarendage P. U. Perera (504811)
Subash Ghimire (5748980)

Open link

Publication date

November 2018

DOI

10.1371/journal.pone.0208421.g004

Publisher

Public Library of Science (PLoS)

Abstract

(A) Genomic structure and histone modification profiles of two alternative promoters (U1 and U2) and the main promoter (E1) of mouse Mest. Genomic positions of U1, U2, E1 and E2 (exon 2) are indicated with vertical lines on the genome browser of UCSC. Histone modification profiles (H3K4me1, H3K4me3, H3K27ac) from embryonic cells (ES), thymus, and brain are presented along with sequence conservation profiles (Mammal Cons). (B) Expression profiles of U1, U2, and E1 of Mest. A set of cDNAs derived from 13 individual tissues was used for RT-PCR surveys monitoring the expression patterns of U1, and U2, and E1 promoters.</p