<p>Transcripts containing the alternative (E1a) and conventional (E1c) exon 1 were amplified using specific primers designed by Gomez-del Arco et al. The levels in each pre-tumor or tumor samples were compared to the average levels in wild type mice obtained from 6 FVB/N (A) and 4 C57BL/6 (B) mice, respectively.</p
Aberrations of Notch signaling in humans cause both congenital and acquired defects and cancers. Gen...
<p><b>A,</b> Western blot analysis showing the up-regulated expression of IKK, p65, and NF-<i>κ</i>B...
<p>Gel electrophoresis RT-PCR results of: (A) Notch pathway gene transcripts - <i>Notch1, Notch2, No...
(A) Genomic structure and histone modification profiles of an alternative promoter (U1) and the main...
<p>DNA samples isolated from individual tumors from indicated transgenic strains were used as templa...
<p>WT = wild-type, C = carrier <i>Sdl</i> thymus, T = tumor. Error bars represent standard deviation...
<p>The expression of Notch1, PCNA, P53, MMP9, PI3K, p-AKT, Bcl-2 and Cyclin D1 in Notch1 siRNA,Notch...
<p><b>A,</b> The expression of Notch ligands and Notch downstream genes was increased at mRNA level ...
(A) Genomic structure and histone modification profiles of an alternative promoter (U1) and the main...
This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Oncogene. ...
T cell lymphoblastic leukemia (T-ALL) is known to be associated with chromosomal abnormalities that ...
<p>Tumor growth in nude mice treated with Notch1 siRNA and Notch2 construct compared to that in cont...
This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Oncogene. ...
<p><b>A,</b> Western blot analysis showing the up-regulated expression of IKK, p65, and NF-κB downst...
<p>B16 melanoma cells were implanted in annexin A1 knockout and wild type mice to grow up tumors. Wh...
Aberrations of Notch signaling in humans cause both congenital and acquired defects and cancers. Gen...
<p><b>A,</b> Western blot analysis showing the up-regulated expression of IKK, p65, and NF-<i>κ</i>B...
<p>Gel electrophoresis RT-PCR results of: (A) Notch pathway gene transcripts - <i>Notch1, Notch2, No...
(A) Genomic structure and histone modification profiles of an alternative promoter (U1) and the main...
<p>DNA samples isolated from individual tumors from indicated transgenic strains were used as templa...
<p>WT = wild-type, C = carrier <i>Sdl</i> thymus, T = tumor. Error bars represent standard deviation...
<p>The expression of Notch1, PCNA, P53, MMP9, PI3K, p-AKT, Bcl-2 and Cyclin D1 in Notch1 siRNA,Notch...
<p><b>A,</b> The expression of Notch ligands and Notch downstream genes was increased at mRNA level ...
(A) Genomic structure and histone modification profiles of an alternative promoter (U1) and the main...
This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Oncogene. ...
T cell lymphoblastic leukemia (T-ALL) is known to be associated with chromosomal abnormalities that ...
<p>Tumor growth in nude mice treated with Notch1 siRNA and Notch2 construct compared to that in cont...
This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Oncogene. ...
<p><b>A,</b> Western blot analysis showing the up-regulated expression of IKK, p65, and NF-κB downst...
<p>B16 melanoma cells were implanted in annexin A1 knockout and wild type mice to grow up tumors. Wh...
Aberrations of Notch signaling in humans cause both congenital and acquired defects and cancers. Gen...
<p><b>A,</b> Western blot analysis showing the up-regulated expression of IKK, p65, and NF-<i>κ</i>B...
<p>Gel electrophoresis RT-PCR results of: (A) Notch pathway gene transcripts - <i>Notch1, Notch2, No...