The levels of tau (A, C, E, G) and AT8-immunopositive phosphorylated tau (B, D, F, H) in the TBS-soluble (A, B, E, F) and sarkosyl-insoluble (C, D, G, H) fractions in the cerebral cortex (A-D) and the hippocampus (E-H) were analyzed in rTg4510_TxC mice fed with control chow diet (n = 4) and rTg4510_CxT mice fed with control chow diet (n = 4). Data are the mean ± standard error of the mean. Significance (Mann Whitney test): *p < 0.05, **p < 0.01.</p
<p>(A, B) Levels of tau dimers (d) in the EC (A) and DG (B) of EC-hTau mice, NTG mice (negative cont...
<p>(A) Immunoblotting analysis was visualized using AT8 antibody for the sarkosyl-insoluble fraction...
<p>(A) Fractionation scheme of total brain homogenates from Tau.P301L mice to generate soluble (S1) ...
(A, D) Representative western blot images for tau and β-actin in the cerebral cortex (A) and the hip...
(A, D) Representative images in western blotting for tau and AT8 in the cerebral cortex (A) and the ...
(A-D) AT8-mmunoreactive area (A, C) and Gallyas positively staining area (B, D) in the cerebral cort...
Representative photographs showing the immunohistochemistry for AT8 (A-D) and Gallyas silver stainin...
Representative photographs showing the immunohistochemistry for AT8 (A-D) and Gallyas silver stainin...
<p><b>A.</b> AT8 p-tau staining in 3- and 6-month old rTg4510 brain sections. Scale bar = 500 μm. <b...
<p>Phosphorylated tau (P-tau) was detected in the hippocampus and cortex of WT/Tg and KO/Tg mice bra...
<p>The frontal cortex from APOE mice were homogenised in sucrose homogenisation buffer, lysates were...
<p>(A) Cortical and (B) hippocampal extracts were prepared from two different 3 and 6-week-old wt an...
<p>A comparable lowering of insoluble tau was obtained by late short-term rapamycin administration o...
<p>(<b>A–F</b>) Representative sections depicting CA1 pyramidal neurons from brains of 3xTg-AD<sup>C...
<p>Brain sections from rTg9191 mice of 24 months of age (B, F, J, N, R, V, Z), their age-matched non...
<p>(A, B) Levels of tau dimers (d) in the EC (A) and DG (B) of EC-hTau mice, NTG mice (negative cont...
<p>(A) Immunoblotting analysis was visualized using AT8 antibody for the sarkosyl-insoluble fraction...
<p>(A) Fractionation scheme of total brain homogenates from Tau.P301L mice to generate soluble (S1) ...
(A, D) Representative western blot images for tau and β-actin in the cerebral cortex (A) and the hip...
(A, D) Representative images in western blotting for tau and AT8 in the cerebral cortex (A) and the ...
(A-D) AT8-mmunoreactive area (A, C) and Gallyas positively staining area (B, D) in the cerebral cort...
Representative photographs showing the immunohistochemistry for AT8 (A-D) and Gallyas silver stainin...
Representative photographs showing the immunohistochemistry for AT8 (A-D) and Gallyas silver stainin...
<p><b>A.</b> AT8 p-tau staining in 3- and 6-month old rTg4510 brain sections. Scale bar = 500 μm. <b...
<p>Phosphorylated tau (P-tau) was detected in the hippocampus and cortex of WT/Tg and KO/Tg mice bra...
<p>The frontal cortex from APOE mice were homogenised in sucrose homogenisation buffer, lysates were...
<p>(A) Cortical and (B) hippocampal extracts were prepared from two different 3 and 6-week-old wt an...
<p>A comparable lowering of insoluble tau was obtained by late short-term rapamycin administration o...
<p>(<b>A–F</b>) Representative sections depicting CA1 pyramidal neurons from brains of 3xTg-AD<sup>C...
<p>Brain sections from rTg9191 mice of 24 months of age (B, F, J, N, R, V, Z), their age-matched non...
<p>(A, B) Levels of tau dimers (d) in the EC (A) and DG (B) of EC-hTau mice, NTG mice (negative cont...
<p>(A) Immunoblotting analysis was visualized using AT8 antibody for the sarkosyl-insoluble fraction...
<p>(A) Fractionation scheme of total brain homogenates from Tau.P301L mice to generate soluble (S1) ...