(A, D) Representative western blot images for tau and β-actin in the cerebral cortex (A) and the hippocampus (D). Left and right bands in each group correspond to rTg4510_TxC mice and rTg4510_CxT mice, respectively. (B, C, E, F) Densitometric analysis of the levels of tau and AT8-positive phosphorylated tau in the cerebral cortex (B, C) and the hippocampus (E, F) in rTg4510 mice fed with control chow diet (n = 8) and Shiga-Y5 (SY5)-containing chow diet (n = 7). Data are the mean ± standard error of the mean. Significance (Mann Whitney test): *p < 0.05.</p
<p>Top panels illustrate <i>p</i>-tau IR in the hippocampus of 9 month old (<b>A</b> vs <b>B)</b> an...
The rTg4510 mouse overexpresses an inducible human mutant tau (TauP301L) selectively in the forebrai...
<p><b>A</b>. Representative photomicrographs (frontal cortex) of brain sections from the higher expr...
The levels of tau (A, C, E, G) and AT8-immunopositive phosphorylated tau (B, D, F, H) in the TBS-sol...
(A, D) Representative images in western blotting for tau and AT8 in the cerebral cortex (A) and the ...
(A-D) AT8-mmunoreactive area (A, C) and Gallyas positively staining area (B, D) in the cerebral cort...
Representative photographs showing the immunohistochemistry for AT8 (A-D) and Gallyas silver stainin...
Representative photographs showing the immunohistochemistry for AT8 (A-D) and Gallyas silver stainin...
<p>(<b>A</b>) Representative western blots showing GSK3β, phosphorylated GSK-3 (pSer9-GSK3β), AKT, p...
<p><b>A.</b> AT8 p-tau staining in 3- and 6-month old rTg4510 brain sections. Scale bar = 500 μm. <b...
<p>Phosphorylated tau (P-tau) was detected in the hippocampus and cortex of WT/Tg and KO/Tg mice bra...
<p>(A) Cortical and (B) hippocampal extracts were prepared from two different 3 and 6-week-old wt an...
<p>Brain sections from rTg9191 mice of 24 months of age (B, F, J, N, R, V, Z), their age-matched non...
<p>(<b>A–F</b>) Representative sections depicting CA1 pyramidal neurons from brains of 3xTg-AD<sup>C...
<p>The frontal cortex from APOE mice were homogenised in sucrose homogenisation buffer, lysates were...
<p>Top panels illustrate <i>p</i>-tau IR in the hippocampus of 9 month old (<b>A</b> vs <b>B)</b> an...
The rTg4510 mouse overexpresses an inducible human mutant tau (TauP301L) selectively in the forebrai...
<p><b>A</b>. Representative photomicrographs (frontal cortex) of brain sections from the higher expr...
The levels of tau (A, C, E, G) and AT8-immunopositive phosphorylated tau (B, D, F, H) in the TBS-sol...
(A, D) Representative images in western blotting for tau and AT8 in the cerebral cortex (A) and the ...
(A-D) AT8-mmunoreactive area (A, C) and Gallyas positively staining area (B, D) in the cerebral cort...
Representative photographs showing the immunohistochemistry for AT8 (A-D) and Gallyas silver stainin...
Representative photographs showing the immunohistochemistry for AT8 (A-D) and Gallyas silver stainin...
<p>(<b>A</b>) Representative western blots showing GSK3β, phosphorylated GSK-3 (pSer9-GSK3β), AKT, p...
<p><b>A.</b> AT8 p-tau staining in 3- and 6-month old rTg4510 brain sections. Scale bar = 500 μm. <b...
<p>Phosphorylated tau (P-tau) was detected in the hippocampus and cortex of WT/Tg and KO/Tg mice bra...
<p>(A) Cortical and (B) hippocampal extracts were prepared from two different 3 and 6-week-old wt an...
<p>Brain sections from rTg9191 mice of 24 months of age (B, F, J, N, R, V, Z), their age-matched non...
<p>(<b>A–F</b>) Representative sections depicting CA1 pyramidal neurons from brains of 3xTg-AD<sup>C...
<p>The frontal cortex from APOE mice were homogenised in sucrose homogenisation buffer, lysates were...
<p>Top panels illustrate <i>p</i>-tau IR in the hippocampus of 9 month old (<b>A</b> vs <b>B)</b> an...
The rTg4510 mouse overexpresses an inducible human mutant tau (TauP301L) selectively in the forebrai...
<p><b>A</b>. Representative photomicrographs (frontal cortex) of brain sections from the higher expr...