B cells can attain CD8 phenotype in vitro.
- Ulrike Strittmatter-Keller (6078497)
- Caroline Walter (6078500)
- Celine Rauld (1697938)
- Nicole Egli (824646)
- Camille Regairaz (6078503)
- Sabine Rabe (6078506)
- Gerhard Zenke (2342968)
- José Carballido (6078509)
- Tamás Schweighoffer (6078512)
Publication date
December 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
Conversion of B cells to the CD8+ phenotype was measured by FACS analysis of in vitro PBMC cultures at 0, 4, 20, and 72h. Left column: CD8+CD19+ cells mapped as red dots to the CD27/CD200 space. Middle column: CD8 expression of all CD19+ B lymphocytes, with numbers indicating the percentage of positives (defined as falling into the gate represented by the grey area). Right column: CD8 expression of gated CD19+CD27+CD200- B lymphocytes, with numbers indicating the percentage of positives. Data from one representative donor material out of four tested shown.</p
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