Restoration of AMPKα1 rescued the phenotypes generated by EBV-miR-BART1-5P.
- Xiaoming Lyu (417710)
- Jianguo Wang (1400488)
- Xia Guo (486444)
- Gongfa Wu (6091571)
- Yang Jiao (147576)
- Oluwasijibomi Damola Faleti (6091574)
- Pengfei Liu (136115)
- Tielian Liu (6091577)
- Yufei Long (6091580)
- Tuotuo Chong (6091583)
- Xu Yang (112496)
- Jing Huang (41604)
- Mingliang He (2831675)
- Chi Man Tsang (155945)
- Sai Wah Tsao (123629)
- Qian Wang (32718)
- Qiang Jiang (764314)
- Xin Li (51274)
Publication date
December 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) Lactate production and glucose consumption, (B) CAM angiogenesis, (C) colony formation detected in HONE-BART1-5P cells after transfection AMPKα1 plasmid, PTEN plasmid and both of them. The data were shown as the mean ± s.e.m. (*PD) AMPKα1, mTOR, p- mTOR, S6K1, VEGF, HIF-1α, GLUT1, LDHA, CCND1, P27 and p21 protein expression levels in HONE-BART1-5P cells treated with AMPKα1 plasmid, PTEN plasmid and both of them. β-actin was used as a loading control. (E) Ki-67 and CD31 expression was detected using immunohistochemistry assay in tumour tissues derived from tumorigenesis in nude mice models. Magnification, ×400.</p
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