Intracellular, extracellular (A) or exosomal (B) miR-8073 expression in 6x104colorectal cancer cell HCT116 and normal cell HCoEpic. In Fig 1B, exosomes that were extracted from the same amount of the cell cultured supernatant used in Fig 1A, were assayed for microRNA expression profiling. MiR-8073 was one of microRNAs that was most exported to extracellular space in the cancer cells but much less in the normal cells. The error bar indicates standard deviation. The star indicates p<0.05 in student’s t-test.</p
The release of molecules in exosomal cargoes is involved in tumor development and progression. We co...
The release of molecules in exosomal cargoes is involved in tumor development and progression. We co...
<p>(A) Cellular viability (MTT assay): Data are presented as ±sd. of at least 3 independent experime...
Administration of miR-8073 mimic significantly reduced colorectal tumor volume (A) and weight (B) in...
The comprehensive screening of intracellular and extracellular microRNAs was performed to identify n...
The comprehensive screening of intracellular and extracellular microRNAs was performed to identify n...
BACKGROUND: Cells release extracellular membrane vesicles including microvesicles known as exosomes....
BACKGROUND: Cells release extracellular membrane vesicles including microvesicles known as exosomes....
Exosomes are a group of small membranous vesicles that are shed into the extracellular environment b...
<p>Oncomirs belonging to the miR-17-92 cluster were analyzed for expression. (A) Box plot showing th...
Viability of human colorectal cancer cells HCT116, and (B) other types of cancer cells or normal cel...
Exosomes are a group of small membranous vesicles that are shed into the extracellular environment b...
BACKGROUND: Exosomes play a major role in cell-to-cell communication, targeting cells to transfer ex...
Exosomes play a major role in cell-to-cell communication, targeting cells to transfer exosomal molec...
MicroRNAs (miRNAs) constitute a large family of small, approximately 20–22-nucleotide, non-coding RN...
The release of molecules in exosomal cargoes is involved in tumor development and progression. We co...
The release of molecules in exosomal cargoes is involved in tumor development and progression. We co...
<p>(A) Cellular viability (MTT assay): Data are presented as ±sd. of at least 3 independent experime...
Administration of miR-8073 mimic significantly reduced colorectal tumor volume (A) and weight (B) in...
The comprehensive screening of intracellular and extracellular microRNAs was performed to identify n...
The comprehensive screening of intracellular and extracellular microRNAs was performed to identify n...
BACKGROUND: Cells release extracellular membrane vesicles including microvesicles known as exosomes....
BACKGROUND: Cells release extracellular membrane vesicles including microvesicles known as exosomes....
Exosomes are a group of small membranous vesicles that are shed into the extracellular environment b...
<p>Oncomirs belonging to the miR-17-92 cluster were analyzed for expression. (A) Box plot showing th...
Viability of human colorectal cancer cells HCT116, and (B) other types of cancer cells or normal cel...
Exosomes are a group of small membranous vesicles that are shed into the extracellular environment b...
BACKGROUND: Exosomes play a major role in cell-to-cell communication, targeting cells to transfer ex...
Exosomes play a major role in cell-to-cell communication, targeting cells to transfer exosomal molec...
MicroRNAs (miRNAs) constitute a large family of small, approximately 20–22-nucleotide, non-coding RN...
The release of molecules in exosomal cargoes is involved in tumor development and progression. We co...
The release of molecules in exosomal cargoes is involved in tumor development and progression. We co...
<p>(A) Cellular viability (MTT assay): Data are presented as ±sd. of at least 3 independent experime...