MicroRNA-8073: Tumor suppressor and potential therapeutic treatment - Fig 7

Administration of miR-8073 mimic significantly reduced colorectal tumor volume (A) and weight (B) in xenografted mice. BALB/c nude mice was transplanted with 5x106 HCT116 cells two days before the treatment. The mice were treated with either 2nmol of miR-8073 mimic or microRNA negative control (miR-NC) mixed with atelocollagen at the day 0, 2, 5 (arrows). The tumor weight (B) was measured at the day 13. The error bars indicate the standard error in five mice per treatment group. The star indicates p<0.05 in student’s t-test.