The GP5-Mosaic vaccine induced wider recall cellular responses <i>ex vivo</i> than the GP5-WT vaccine.
- Junru Cui (6281480)
- Caitlin M. O’Connell (6281483)
- Antonio Costa (2453434)
- Yan Pan (5477)
- Joan A. Smyth (6281486)
- Paulo H. Verardi (473579)
- Diane J. Burgess (2068993)
- Herbert J. Van Kruiningen (6281489)
- Antonio E. Garmendia (6281492)
Publication date
January 2019
DOI Publisher
Public Library of Science (PLoS)Abstract
A. IFN-γ mRNA fold changes in PBMCs of empty vector control pigs; B. IFN-γ mRNA fold changes in PBMCs of GP5-WT vaccinated pigs; C. IFN-γ mRNA fold changes in PBMCs of GP5-Mosaic vaccinated pigs. IFN-γ mRNA fold changes in PBMCs at days 0, challenge and 4DPC in response to VR2332, NADC9, NADC30 and SDSU73. Fold increase less than 2 was not considered as real change. Each bar represents the mean value of each group. Variation is expressed as standard error of the mean. Three replicate experiments were performed. Significant differences were calculated by a student t test (p<0.05*). (DPC: days post challenge). Significant fold-increases are by comparison with day 0 (asterisks).</p
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