MOESM6 of Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

Additional file 6. Use of whole-body bioluminescence signal measurement to animal death in the modified Thompson test studies. Mice 1–5 belonged to a study group which was given 20 mg/kg of a potential antimalarial compound on days 3, 4, and 5 post infections with 1 × 105 P. berghei infected RBC’s. Whole-body bioluminescence values marked in green show the day in which these mice could have been euthanized based in the new criteria for using PLPP to predict animal death in study mice (bioluminescence signal ≥ 1.5 × 109 photons/s). Cells marked in yellow show the day in which these mice were euthanized based on euthanization criteria described in Additional file 1