Two macaques #T769 (blue), T770 (red) received two 5mg/kg injections SC six weeks apart (arrows). Animals were bled at the days indicated and assessed for serum PGT121 levels by ELISA. The green line is an average of two macaques after a single injection of unmodified PGT121 (24).</p
Broadly neutralising antibodies (bNAbs) may play an important role in future strategies for HIV cont...
<p>GLP2-2G-XTEN plasma concentration is shown following 25 nmol/kg administration via intravenous (t...
<p>Plasma concentration of ST-246 after a single oral dose of 3 (chartreuse hexagons), 10 (purple sq...
Four macaques received a SC injection of 5mg/kg and were bled and assayed for circulating PGT121-YTE...
<p>Data are an average of two macaques. Each pharmacokinetics study was repeated once or twice. (A) ...
Pharmacokinetic parameters in four macaques following a single SC injection with 5mg/kg PGT121-YTE.<...
Macaques #T769 (blue bars) and # T770 (red bars) from Fig 3 were injected SC with 5mg/kg of PGT121-Y...
Four macaques received 5mg/kg of PGT121-YTE SC. Two macaques #T766 (dark green) and #13D036 (light g...
Macaques #12N010 (left) and #JFL (right) were injected twice SC with 5mg/kg PGT121 eight weeks apart...
Two monkeys were each injected twice with PGT121-YTE (arrows) and bled at the times indicated. Sera ...
<p>NKTT120 plasma concentrations were measured by ELISA. Shown are means within groups with standard...
<p>(A) Plasma samples from the 11 macaques injected (color coded) were collected 2–3 weeks following...
The coloured bars depict binding ADA at OD450 (left axis) at different times after challenge. Black ...
<p>The numbers of the six macaques injected (2 macaques/gp in three different studies) are indicated...
<p>mDC counts are illustrated as a percentage of the baseline mDC counts recorded prior to SIVagmSab...
Broadly neutralising antibodies (bNAbs) may play an important role in future strategies for HIV cont...
<p>GLP2-2G-XTEN plasma concentration is shown following 25 nmol/kg administration via intravenous (t...
<p>Plasma concentration of ST-246 after a single oral dose of 3 (chartreuse hexagons), 10 (purple sq...
Four macaques received a SC injection of 5mg/kg and were bled and assayed for circulating PGT121-YTE...
<p>Data are an average of two macaques. Each pharmacokinetics study was repeated once or twice. (A) ...
Pharmacokinetic parameters in four macaques following a single SC injection with 5mg/kg PGT121-YTE.<...
Macaques #T769 (blue bars) and # T770 (red bars) from Fig 3 were injected SC with 5mg/kg of PGT121-Y...
Four macaques received 5mg/kg of PGT121-YTE SC. Two macaques #T766 (dark green) and #13D036 (light g...
Macaques #12N010 (left) and #JFL (right) were injected twice SC with 5mg/kg PGT121 eight weeks apart...
Two monkeys were each injected twice with PGT121-YTE (arrows) and bled at the times indicated. Sera ...
<p>NKTT120 plasma concentrations were measured by ELISA. Shown are means within groups with standard...
<p>(A) Plasma samples from the 11 macaques injected (color coded) were collected 2–3 weeks following...
The coloured bars depict binding ADA at OD450 (left axis) at different times after challenge. Black ...
<p>The numbers of the six macaques injected (2 macaques/gp in three different studies) are indicated...
<p>mDC counts are illustrated as a percentage of the baseline mDC counts recorded prior to SIVagmSab...
Broadly neutralising antibodies (bNAbs) may play an important role in future strategies for HIV cont...
<p>GLP2-2G-XTEN plasma concentration is shown following 25 nmol/kg administration via intravenous (t...
<p>Plasma concentration of ST-246 after a single oral dose of 3 (chartreuse hexagons), 10 (purple sq...