BED files. This folder contains the input-normalized 2C-ChIP data in BedGraph format of all the ChIP samples measured in this study. BED files 1 and 2: H3K4me3 in untreated (0h; 1) and RA-treated (3d; 2) NT2-D1 (setA). BED files 3 and 4: H3K27me3 in untreated (0h; 3) and RA-treated (3d; 4) NT2-D1 (setA). BED files 5 and 6: SUZ12 in untreated (0h; 5) and RA-treated (3d; 6) NT2-D1 (setA). BED files 7, 8, 9, and 10: H3K4me3 in untreated (0h; 7) and RA-treated (6h; 8, 3d; 9, 7d; 10) NT2-D1 (setB). BED files 11, 12, 13, and 14: Ash2L in untreated (0h; 11) and RA-treated (6h; 12, 3d; 13, 7d; 14) NT2-D1 (setB). BED files 15, 16, 17, and 18: H3K27me3 in untreated (0h; 15) and RA-treated (6h; 16, 3d; 17, 7d; 18) NT2-D1 (setB). BED files 19, 20, 21, ...
Clinical trial BR9601 information. (a) Schematic representation. (b) Patient information. Figure S2....
Setup of chromatin preparation conditions. Table S1. ChIP-qPCR primers. Table S2. Quantity of chroma...
Additional Figures S1-S10. Chromosomal aberration in HNSCC patient derived cell lines AW8507, AW1351...
Figure S6. 2C-ChIP results for Ash2L, CTCF, and UTX in set A. Data is displayed as outlined in Fig. ...
Figure S5. Comparison of two biological replicates shows that 2C-ChIP is highly reproducible. The un...
5C datasets. This folder contains the read count-normalized 5C data in matrix format (.txt) of all t...
Figure S1. SUZ12 binding analysis by 2C-ChIP and ChIP-qPCR correlate well at the HOXA cluster. a 2C-...
Figure S2. Defining the optimal 2C-ChIP linear detection range. a Diagram of the HOXA cluster region...
Table S5. List of primer sequences used to amplify 2C-ChIP libraries prior to deep sequencing on a P...
Table S6. List of primer sequences used for chromatin conformation capture carbon copy (5C). (XLSX 1...
Figure S3. The basal and 3-day induced gene expression levels from two biological replicates correla...
Table S3. List of primer sequences used to PCR-quantify DNA regions isolated by chromatin immunoprec...
Table S1. HOXA and lncRNA gene expression in NT2-D1 cells before and after a 3-day treatment with re...
Figure S7. RA-induced NT2-D1 differentiation is accompanied by extensive conformational and epigenom...
ChIP enrichment analyzed by qPCR. The ChIP DNA was analyzed by qPCR in a region of constitutively ac...
Clinical trial BR9601 information. (a) Schematic representation. (b) Patient information. Figure S2....
Setup of chromatin preparation conditions. Table S1. ChIP-qPCR primers. Table S2. Quantity of chroma...
Additional Figures S1-S10. Chromosomal aberration in HNSCC patient derived cell lines AW8507, AW1351...
Figure S6. 2C-ChIP results for Ash2L, CTCF, and UTX in set A. Data is displayed as outlined in Fig. ...
Figure S5. Comparison of two biological replicates shows that 2C-ChIP is highly reproducible. The un...
5C datasets. This folder contains the read count-normalized 5C data in matrix format (.txt) of all t...
Figure S1. SUZ12 binding analysis by 2C-ChIP and ChIP-qPCR correlate well at the HOXA cluster. a 2C-...
Figure S2. Defining the optimal 2C-ChIP linear detection range. a Diagram of the HOXA cluster region...
Table S5. List of primer sequences used to amplify 2C-ChIP libraries prior to deep sequencing on a P...
Table S6. List of primer sequences used for chromatin conformation capture carbon copy (5C). (XLSX 1...
Figure S3. The basal and 3-day induced gene expression levels from two biological replicates correla...
Table S3. List of primer sequences used to PCR-quantify DNA regions isolated by chromatin immunoprec...
Table S1. HOXA and lncRNA gene expression in NT2-D1 cells before and after a 3-day treatment with re...
Figure S7. RA-induced NT2-D1 differentiation is accompanied by extensive conformational and epigenom...
ChIP enrichment analyzed by qPCR. The ChIP DNA was analyzed by qPCR in a region of constitutively ac...
Clinical trial BR9601 information. (a) Schematic representation. (b) Patient information. Figure S2....
Setup of chromatin preparation conditions. Table S1. ChIP-qPCR primers. Table S2. Quantity of chroma...
Additional Figures S1-S10. Chromosomal aberration in HNSCC patient derived cell lines AW8507, AW1351...