Table S6. Analysis of candidate gene probes in an independent methylation array dataset (GSE73549). (XLSX 20 kb
Figure S5. Heatmap showing expression of all differentially expressed and downregulated genes in bot...
Figure S11. Methylation of ASB2 is increased in both knockouts (CR1 and CR2) within the TET2-knockou...
Figure S1. CRISPR-TET2 guide RNA targets the first coding exon of TET2. Arrows indicate the CRISPR t...
Table S5. Association of candidate gene probe methylation with ERG fusion status. (XLSX 19 kb
Table S2. Genes exhibiting both significantly increased promoter methylation and significantly lower...
Table S7. Clinicopathological characteristics of prostate tumor tissues used for methylation analysi...
Table S3. Characteristics of the 61 genes exhibiting significantly increased promoter methylation an...
Figure S10. Heatmap showing methylation of seven candidate genes for all tumor (n = 428) and normal ...
Table S1. Primer and probe sequences used for CRISPR verification and methylation-specific qPCR. (XL...
Figure S9. Methylation array probe locations on candidate genes with respect to the TET2-knockout me...
Table S4. Expression of candidate genes significantly associated with ERG fusion status. (XLSX 18 kb
Figure S13. Diagnostic enrichment plot of MBD-Seq samples from TET2-KO cells as compared to input co...
Figure S7. Pathway enrichment analysis of genes losing expression in CRISPR-TET2 knockout cells. Vis...
Figure S6. Heatmap showing expression of 780 genes which exhibited significant expression alteration...
Figure S14. Multidimensional scaling (MDS) plot depicting Euclidean distances (similarities) between...
Figure S5. Heatmap showing expression of all differentially expressed and downregulated genes in bot...
Figure S11. Methylation of ASB2 is increased in both knockouts (CR1 and CR2) within the TET2-knockou...
Figure S1. CRISPR-TET2 guide RNA targets the first coding exon of TET2. Arrows indicate the CRISPR t...
Table S5. Association of candidate gene probe methylation with ERG fusion status. (XLSX 19 kb
Table S2. Genes exhibiting both significantly increased promoter methylation and significantly lower...
Table S7. Clinicopathological characteristics of prostate tumor tissues used for methylation analysi...
Table S3. Characteristics of the 61 genes exhibiting significantly increased promoter methylation an...
Figure S10. Heatmap showing methylation of seven candidate genes for all tumor (n = 428) and normal ...
Table S1. Primer and probe sequences used for CRISPR verification and methylation-specific qPCR. (XL...
Figure S9. Methylation array probe locations on candidate genes with respect to the TET2-knockout me...
Table S4. Expression of candidate genes significantly associated with ERG fusion status. (XLSX 18 kb
Figure S13. Diagnostic enrichment plot of MBD-Seq samples from TET2-KO cells as compared to input co...
Figure S7. Pathway enrichment analysis of genes losing expression in CRISPR-TET2 knockout cells. Vis...
Figure S6. Heatmap showing expression of 780 genes which exhibited significant expression alteration...
Figure S14. Multidimensional scaling (MDS) plot depicting Euclidean distances (similarities) between...
Figure S5. Heatmap showing expression of all differentially expressed and downregulated genes in bot...
Figure S11. Methylation of ASB2 is increased in both knockouts (CR1 and CR2) within the TET2-knockou...
Figure S1. CRISPR-TET2 guide RNA targets the first coding exon of TET2. Arrows indicate the CRISPR t...
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