Conditional ablation of ChAT in T-cells increases C. rodentium-induced innate inflammatory genes.
- Valerie T. Ramirez (474026)
- Dayn R. Godinez (6623513)
- Ingrid Brust-Mascher (52631)
- Eric B. Nonnecke (4759920)
- Patricia A. Castillo (128473)
- Mariana Barboza Gardner (6580943)
- Diane Tu (6580946)
- Jessica A. Sladek (6580949)
- Elaine N. Miller (6623516)
- Carlito B. Lebrilla (223528)
- Charles L. Bevins (128491)
- Melanie G. Gareau (403140)
- Colin Reardon (4285078)
Publication date
April 2019
DOI Publisher
Public Library of Science (PLoS)Abstract
The immune response during infection was assessed through qRT-PCR conducted on colonic tissues from LB or C. rodentium infected WT or ChAT T-cell cKO mice. Expression of the cytokines Il1-β, Il-6, and Tnfα, Ifnγ, Il-17a and Il-22 was evaluated in naïve and infected WT and ChAT T-cell cKO mice. *, # P < 0.05 ANOVA, with n = 8–10 mice per group.</p
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