Mean enrichment of predicted (A) OGs and (B) TS and LOFs with experimental data. The error bars show the standard deviation across GEMs generated with general and cell-specific media. Hypergeometric p-values are shown above each figure. Model fraction represents the fraction of generated GEMs with significant p-values (<0.05). Only methods with significant predictions are shown.</p
The disease prediction data showing the accuracy, sensitivity, and the selectivity of Seq-GNM compar...
All somatic mutations are annotated using OncoKB to determine predicted oncogenecity. Projects are o...
(A) CORDA, (B) FASTCORMICS, (C) GIMME, (D) PRIME, (E) TRFBA, and (F) iMAT. Only GEMs capable of pred...
(A) Heatmap of enrichment p-values for predicted cell-line specific essential genes. The numbers ind...
GEMs_PCAWG: 943 cancer patient-specific genome-scale metabolic models (GEMs) for 24 different cancer...
<p>Tumor zygosity predictions of somatic mutations in 20,182 clinical samples.</p
(A-D) Quantification of mis-segregation and turnover rates. (A) Expression of regulators of cell dea...
<p>The predictive models were derived from cell line Oncopanel expression data. Patient data normali...
<p>For each human gene, the expected number of mutations is obtained based on the normal mutation pa...
The predicted (blue markers) and actual proportions (orange markers) of individuals that experience ...
<p>Mutation frequencies as predicted by the generalized linear model (large dots) and observed frequ...
<p><sup>a</sup> Hmax is the maximum OD reached when the curve is saturated.</p><p><sup>b</sup>C50 re...
<p>The top three panels are genes having low-levels gains or high-level amplifications (magenta) com...
<p>A. CHER’s model for drug sensitivity to paclitaxel. Each vertical bar represents a data of a samp...
Survivin (A), CK20 (B), E-Cadherin (C) and CD44 (D) gene expression levels in LG and HG BCs. LG: Low...
The disease prediction data showing the accuracy, sensitivity, and the selectivity of Seq-GNM compar...
All somatic mutations are annotated using OncoKB to determine predicted oncogenecity. Projects are o...
(A) CORDA, (B) FASTCORMICS, (C) GIMME, (D) PRIME, (E) TRFBA, and (F) iMAT. Only GEMs capable of pred...
(A) Heatmap of enrichment p-values for predicted cell-line specific essential genes. The numbers ind...
GEMs_PCAWG: 943 cancer patient-specific genome-scale metabolic models (GEMs) for 24 different cancer...
<p>Tumor zygosity predictions of somatic mutations in 20,182 clinical samples.</p
(A-D) Quantification of mis-segregation and turnover rates. (A) Expression of regulators of cell dea...
<p>The predictive models were derived from cell line Oncopanel expression data. Patient data normali...
<p>For each human gene, the expected number of mutations is obtained based on the normal mutation pa...
The predicted (blue markers) and actual proportions (orange markers) of individuals that experience ...
<p>Mutation frequencies as predicted by the generalized linear model (large dots) and observed frequ...
<p><sup>a</sup> Hmax is the maximum OD reached when the curve is saturated.</p><p><sup>b</sup>C50 re...
<p>The top three panels are genes having low-levels gains or high-level amplifications (magenta) com...
<p>A. CHER’s model for drug sensitivity to paclitaxel. Each vertical bar represents a data of a samp...
Survivin (A), CK20 (B), E-Cadherin (C) and CD44 (D) gene expression levels in LG and HG BCs. LG: Low...
The disease prediction data showing the accuracy, sensitivity, and the selectivity of Seq-GNM compar...
All somatic mutations are annotated using OncoKB to determine predicted oncogenecity. Projects are o...
(A) CORDA, (B) FASTCORMICS, (C) GIMME, (D) PRIME, (E) TRFBA, and (F) iMAT. Only GEMs capable of pred...