Kaplan-Meier survival curves for a selection of top hub glioblastoma genes predicted by the Lemon-Tree algorithm.

<p>The top three panels are genes having low-levels gains or high-level amplifications (magenta) compared to normal (blue), the bottom three panels are genes having single-copy loss or homozygous deletions (green) compared to normal (blue). All genes display significant differences between the groups (p < 0.05, see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003983#pcbi.1003983.s006" target="_blank">S6 Table</a> for a full list of p-values). Patient with putative gene gains or losses have significantly worse prognosis (lower values on the y-axis). The x-axis on all figures represent the time in number of days.