<p>The sample size is 1000. Covariance matrix of 10 traits is similar to that of 10 quantitative traits with between-factor correlation being 0.3 and the within-factor correlation being 0.7. The percentage of the causal variants is 0.2. All causal variants are risk variants.</p
<p>Heritabilities (diagonal in italics), phenotypic (below the diagonal), and genetic correlations (...
<p>Each box corresponds to a different proportion of causal variants involved in the relationship be...
The power to detect a quantitative trait locus (QTL) in sib-pair data is investigated. We assume tha...
<p>The sample size is 1000. The between-factor correlation is 0.3 and the within-factor correlation ...
<p>The figure shows the empirical power given the significance level of 0.05. Top row: 50 variants i...
<p>The figure shows the empirical power given the significance level of 0.05. Top row: 50 variants i...
<p>Power to detect association in a region is shown for the Generalised C-alpha test, SKAT-O and the...
<p><b>a</b>) Univarite analysis of a quantitative trait. <b>b</b>) Univariate analysis of a case-con...
<p>Powers were calculated for nominal α levels 0.05 (left) and 0.01(right) and for dichotomous trait...
<p>The explained variance of the QTL was fixed at 0.1%. For clarity reasons, we have not provided er...
<p>Each box corresponds to a different proportion of causal variants involved in the relationship be...
<p>Analytic locus-wide power at <i>α</i> = 0.05 of the BC-CA (lower bound), collapsing, and summing ...
<p>Heritability comparison between the trait derived by the proposed approach, individual features a...
<p>Powers were calculated for nominal α levels 0.05 (left) and 0.01(right) and for dichotomous trait...
<p>The power was examined on a trait simulated from 15 causative mutations (QTNs). A total of 1000 r...
<p>Heritabilities (diagonal in italics), phenotypic (below the diagonal), and genetic correlations (...
<p>Each box corresponds to a different proportion of causal variants involved in the relationship be...
The power to detect a quantitative trait locus (QTL) in sib-pair data is investigated. We assume tha...
<p>The sample size is 1000. The between-factor correlation is 0.3 and the within-factor correlation ...
<p>The figure shows the empirical power given the significance level of 0.05. Top row: 50 variants i...
<p>The figure shows the empirical power given the significance level of 0.05. Top row: 50 variants i...
<p>Power to detect association in a region is shown for the Generalised C-alpha test, SKAT-O and the...
<p><b>a</b>) Univarite analysis of a quantitative trait. <b>b</b>) Univariate analysis of a case-con...
<p>Powers were calculated for nominal α levels 0.05 (left) and 0.01(right) and for dichotomous trait...
<p>The explained variance of the QTL was fixed at 0.1%. For clarity reasons, we have not provided er...
<p>Each box corresponds to a different proportion of causal variants involved in the relationship be...
<p>Analytic locus-wide power at <i>α</i> = 0.05 of the BC-CA (lower bound), collapsing, and summing ...
<p>Heritability comparison between the trait derived by the proposed approach, individual features a...
<p>Powers were calculated for nominal α levels 0.05 (left) and 0.01(right) and for dichotomous trait...
<p>The power was examined on a trait simulated from 15 causative mutations (QTNs). A total of 1000 r...
<p>Heritabilities (diagonal in italics), phenotypic (below the diagonal), and genetic correlations (...
<p>Each box corresponds to a different proportion of causal variants involved in the relationship be...
The power to detect a quantitative trait locus (QTL) in sib-pair data is investigated. We assume tha...