Albumin nanocarriers, γ- irradiated crosslinked, combined with therapeutic drugs for cancer therapy
- Siri, Macarena
- Achilli, Estefanía Edith
- Grasselli, Mariano
- Alonso, Silvia del Valle
DOIAbstract
Albumin polymeric Nanoparticles (NPs) have opened a great expectancy as for controlled drug delivery due to their therapeutic potency. Concomitantly biodegradable NPs technologies with target linked structures to pave the way of personalised medicine are becoming increasingly important in sight of a therapeutically effective research technology. This is particularly attractive for nanoparticle-based cancer delivery systems, based on the known limitations and efforts to overcome. This new group of gamma irradiated-NPs inherited both the protein delivery properties and robustness of polymer forming structures, and gamma irradiation techniques that leave clean, innocuous and biodegradable NPs. These protein NPs made of serum albumin are referr...
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