临床上常用的一些非抗心律失常药物如抗菌素和抗组胺类药物也可导致QT间期延长甚至尖端扭转型室性心动过速.主要机理与抑制心肌细胞快速激活延迟整流钾电流相关.正常情况下发生概率极低,但当存在各种危险因素时发生率明显增高.主要的危险因素包括基因的易感性如存在亚临床型先天性QT延长综合征或基因的变异、合并用药、老年、女性、低血钾、严重心动过缓、基础心脏疾病和肝肾功能异常等.正确认识其发生机理和相关危险因素,可保证临床医师有效而安全地使用药物.中国科技核心期刊(ISTIC)中国科学引文数据库(CSCD)02184-1873
Long QT syndrome (LQTS) characterized by prolongation of the QT interval, may occur as congenital or...
科学研究費補助金研究成果報告書研究種目: 基盤研究(C)研究期間: 2012～2014課題番号: 24591575研究代表者: 大野 聖子（滋賀医科大学・アジア疫学研究センター・講師）研究分担者: 堀...
Various drugs can be associated with QT prolongation. A prolonged QT interval leads to an increased ...
临床药物的致心律失常作用可见于多种心脏病和非心脏病用药,不同药物间致心律失常作用发生率差异大,有些药物因为致心律失常发生率低,只有在大规模应用于临床后才发现其致心律失常危险性,极易被忽视,因此,对低危...
Drug-induced torsades de pointes (TdP), a life-threatening polymorphic ventricular tachycardia assoc...
近年来，临床实践有许多药物都会导致Q-T间期延长甚至尖端扭转型室性心律失常(TdP)。本文通过对1979年-2013年国内医药期刊公开报道的药物致Q-T间期延长的个案进行统计和分析，总结了56个病例的...
Until recently, cardiac toxicity manifesting in the form of arrhythmias related to QT interval prolo...
Acquired QT syndrome is mainly caused by the administration of drugs that prolong ventricular repola...
The incidence of drug-induced proarrhythmias in the general population is largely unknown. Knowledge...
Cel pracy: Celem pracy była ocena wpływu wybranych parametrów, takich jak wielkość dawki leku przeci...
associated with increased risk of torsade de pointes (TdP), the precise relationship is not well def...
ObjectivesThe goal of this study was to identify markers of torsades de pointes (TdP) in patients wi...
Torsade de pointes (TdP) is a life-threatening arrhythmia that develops as a consequence of a reduct...
Purpose: Drug-induced APD prolongation was first proposed to be antiarrhythmic, but is now widely pr...
Background More than 170 drugs are linked with QTc-prolongation, which in extreme cases can lead to ...
Long QT syndrome (LQTS) characterized by prolongation of the QT interval, may occur as congenital or...
科学研究費補助金研究成果報告書研究種目: 基盤研究(C)研究期間: 2012～2014課題番号: 24591575研究代表者: 大野 聖子（滋賀医科大学・アジア疫学研究センター・講師）研究分担者: 堀...
Various drugs can be associated with QT prolongation. A prolonged QT interval leads to an increased ...
临床药物的致心律失常作用可见于多种心脏病和非心脏病用药,不同药物间致心律失常作用发生率差异大,有些药物因为致心律失常发生率低,只有在大规模应用于临床后才发现其致心律失常危险性,极易被忽视,因此,对低危...
Drug-induced torsades de pointes (TdP), a life-threatening polymorphic ventricular tachycardia assoc...
近年来，临床实践有许多药物都会导致Q-T间期延长甚至尖端扭转型室性心律失常(TdP)。本文通过对1979年-2013年国内医药期刊公开报道的药物致Q-T间期延长的个案进行统计和分析，总结了56个病例的...
Until recently, cardiac toxicity manifesting in the form of arrhythmias related to QT interval prolo...
Acquired QT syndrome is mainly caused by the administration of drugs that prolong ventricular repola...
The incidence of drug-induced proarrhythmias in the general population is largely unknown. Knowledge...
Cel pracy: Celem pracy była ocena wpływu wybranych parametrów, takich jak wielkość dawki leku przeci...
associated with increased risk of torsade de pointes (TdP), the precise relationship is not well def...
ObjectivesThe goal of this study was to identify markers of torsades de pointes (TdP) in patients wi...
Torsade de pointes (TdP) is a life-threatening arrhythmia that develops as a consequence of a reduct...
Purpose: Drug-induced APD prolongation was first proposed to be antiarrhythmic, but is now widely pr...
Background More than 170 drugs are linked with QTc-prolongation, which in extreme cases can lead to ...
Long QT syndrome (LQTS) characterized by prolongation of the QT interval, may occur as congenital or...
科学研究費補助金研究成果報告書研究種目: 基盤研究(C)研究期間: 2012～2014課題番号: 24591575研究代表者: 大野 聖子（滋賀医科大学・アジア疫学研究センター・講師）研究分担者: 堀...
Various drugs can be associated with QT prolongation. A prolonged QT interval leads to an increased ...
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