<i>Zip14</i><sup><i>fl/-</i></sup><i>; Runx2-Cre</i> mice have a severe cortical and trabecular long bone phenotype, whereas <i>Zip14</i><sup><i>fl/-</i></sup><i>; CtsK-Cre</i> mice do not.
- Gretl Hendrickx (5066234)
- Vere M. Borra (5066231)
- Ellen Steenackers (5066219)
- Timur A. Yorgan (4557115)
- Christophe Hermans (5066228)
- Eveline Boudin (5066225)
- Jérôme J. Waterval (5066240)
- Ineke D. C. Jansen (5066222)
- Tolunay Beker Aydemir (125630)
- Niels Kamerling (5066213)
- Geert J. Behets (630682)
- Christine Plumeyer (5066237)
- Patrick C. D’Haese (700370)
- Björn Busse (126702)
- Vincent Everts (197636)
- Martin Lammens (190864)
- Geert Mortier (25729)
- Robert J. Cousins (125638)
- Thorsten Schinke (126724)
- Robert J. Stokroos (2625307)
- Johannes J. Manni (227358)
- Wim Van Hul (5066216)
DOIAbstract
<p><b>(A)</b> 3D reconstruction of whole femora (top) and a vertical section of cortical (middle) and trabecular bone (bottom) of <i>Zip14</i><sup><i>fl/-</i></sup> controls, <i>Zip14</i><sup><i>fl/-</i></sup><i>; Runx2-Cre</i> and <i>Zip14</i><sup><i>fl/-</i></sup><i>; CtsK-Cre</i> mice. Femora of <i>Zip14</i><sup><i>fl/-</i></sup><i>; Runx2-Cre</i> mice show an increased cortical thickness and decreased midshaft diameter along with a decreased trabecular bone mass. <b>(B) μ</b>CT analysis of cortical (Ct) bone parameters confirms a significantly increased cortical thickness (Ct.Th) and decreased midshaft diameter (Ms.D) of <i>Zip14</i><sup><i>fl/-</i></sup><i>; Runx2-Cre</i> mice. Both <i>Zip14</i><sup><i>fl/-</i></sup><i>; Runx2-Cre</i> ...
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