The present sequential mixed-methods project was conducted in the area of clinical psychology of religion and existential health. The central aim of the project was to investigate clinically relevant areas for an assessment of protective and risk factors for existential vulnerability and dysfunctional existential meaning-making in a clinical sample of young women with mental ill-health concerns. Three theoretical areas were applied and operationalized for the project: Existential meaning-making; Ontological security; and, Emotion regulation. The sample was composed of female participants at an outpatient psychodynamic psychotherapy clinic for young adults in Sweden, with depression as the most common preliminary diagnosis. Study I, quantita...