harvested 3 wks after the first injection. Dystrophin immunolabeling (Hoechst dye counterstained) at 2 different magnifications and H&E staining of serial transverse sections from TA muscles from the following groups: normal age-matched controls, untreated, injected with PEI2K(PEG550)-ESO, injected with NG-PEI2K(PEG550)-ESO, and injected with CG-PEI2K(PEG5K)-ESO.<p><b>Copyright information:</b></p><p>Taken from "Nanopolymers improve delivery of exon skipping oligonucleotides and concomitant dystrophin expression in skeletal muscle of mice"</p><p>http://www.biomedcentral.com/1472-6750/8/35</p><p>BMC Biotechnology 2008;8():35-35.</p><p>Published online 2 Apr 2008</p><p>PMCID:PMC2362111.</p><p></p
Duchenne muscular dystrophy (DMD) is a severe hereditary neurodegenerative disorder due to mutations...
Antisense oligonucleotides (AONs) are being developed as RNA therapeutic molecules for Duchenne musc...
AbstractThe use of antisense oligonucleotides (AOs) to induce exon skipping leading to generation of...
harvested 3 wks after the first injection. Dystrophin immunolabeling (Hoechst dye counterstained) at...
�g of ESO per injection (3, 15, 30, and 60 μg total) and harvested 3 wks after the first injection. ...
EG550), or CG-PEI2K(PEG5K)copolymers, and harvested 3 wks after the first injection. Number of dystr...
EG550), or CG-PEI2K(PEG5K)copolymers, and harvested 3 wks after the first injection. Number of dystr...
Ons of either 1 μg () or 5 μg () of ESO complexed with the NG-PEI2K(PEG550)copolymer. Muscles were h...
Ssion. TA muscles were given 10 twice-weekly intramuscular injections of 5 μg of ESO complexed with ...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
Duchenne muscular dystrophy (DMD) is a severe hereditary neuromuscular disorder caused by mutations ...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
Abstract Duchenne muscular dystrophy (DMD) is a severe hereditary neuromuscular disorder caused by m...
Duchenne muscular dystrophy (DMD) is a genetic disease caused by a mutation in the X-linked Dytrophi...
Duchenne muscular dystrophy (DMD) is a severe hereditary neurodegenerative disorder due to mutations...
Antisense oligonucleotides (AONs) are being developed as RNA therapeutic molecules for Duchenne musc...
AbstractThe use of antisense oligonucleotides (AOs) to induce exon skipping leading to generation of...
harvested 3 wks after the first injection. Dystrophin immunolabeling (Hoechst dye counterstained) at...
�g of ESO per injection (3, 15, 30, and 60 μg total) and harvested 3 wks after the first injection. ...
EG550), or CG-PEI2K(PEG5K)copolymers, and harvested 3 wks after the first injection. Number of dystr...
EG550), or CG-PEI2K(PEG5K)copolymers, and harvested 3 wks after the first injection. Number of dystr...
Ons of either 1 μg () or 5 μg () of ESO complexed with the NG-PEI2K(PEG550)copolymer. Muscles were h...
Ssion. TA muscles were given 10 twice-weekly intramuscular injections of 5 μg of ESO complexed with ...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
Duchenne muscular dystrophy (DMD) is a severe hereditary neuromuscular disorder caused by mutations ...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
Abstract Duchenne muscular dystrophy (DMD) is a severe hereditary neuromuscular disorder caused by m...
Duchenne muscular dystrophy (DMD) is a genetic disease caused by a mutation in the X-linked Dytrophi...
Duchenne muscular dystrophy (DMD) is a severe hereditary neurodegenerative disorder due to mutations...
Antisense oligonucleotides (AONs) are being developed as RNA therapeutic molecules for Duchenne musc...
AbstractThe use of antisense oligonucleotides (AOs) to induce exon skipping leading to generation of...