�g of ESO per injection (3, 15, 30, and 60 μg total) and harvested 3 wks after the first injection. Images show dystrophin immunolabeling (Hoechst dye counterstained) and H&E staining of serial transverse sections from TA muscles for each of the 4 polyplex doses.<p><b>Copyright information:</b></p><p>Taken from "Nanopolymers improve delivery of exon skipping oligonucleotides and concomitant dystrophin expression in skeletal muscle of mice"</p><p>http://www.biomedcentral.com/1472-6750/8/35</p><p>BMC Biotechnology 2008;8():35-35.</p><p>Published online 2 Apr 2008</p><p>PMCID:PMC2362111.</p><p></p
Duchenne muscular dystrophy (DMD) is a severe hereditary neurodegenerative disorder due to mutations...
Mingxing Wang, Bo Wu, Jason D Tucker, Peijuan Lu, Qilong Lu Department of Neurology, McColl-Lockwoo...
AbstractThe use of antisense oligonucleotides (AOs) to induce exon skipping leading to generation of...
harvested 3 wks after the first injection. Dystrophin immunolabeling (Hoechst dye counterstained) at...
harvested 3 wks after the first injection. Dystrophin immunolabeling (Hoechst dye counterstained) at...
Ons of either 1 μg () or 5 μg () of ESO complexed with the NG-PEI2K(PEG550)copolymer. Muscles were h...
Ssion. TA muscles were given 10 twice-weekly intramuscular injections of 5 μg of ESO complexed with ...
EG550), or CG-PEI2K(PEG5K)copolymers, and harvested 3 wks after the first injection. Number of dystr...
EG550), or CG-PEI2K(PEG5K)copolymers, and harvested 3 wks after the first injection. Number of dystr...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
Duchenne muscular dystrophy (DMD) is a severe hereditary neuromuscular disorder caused by mutations ...
Abstract Duchenne muscular dystrophy (DMD) is a severe hereditary neuromuscular disorder caused by m...
Duchenne muscular dystrophy (DMD) is a genetic disease caused by a mutation in the X-linked Dytrophi...
Duchenne muscular dystrophy (DMD) is a severe hereditary neurodegenerative disorder due to mutations...
Mingxing Wang, Bo Wu, Jason D Tucker, Peijuan Lu, Qilong Lu Department of Neurology, McColl-Lockwoo...
AbstractThe use of antisense oligonucleotides (AOs) to induce exon skipping leading to generation of...
harvested 3 wks after the first injection. Dystrophin immunolabeling (Hoechst dye counterstained) at...
harvested 3 wks after the first injection. Dystrophin immunolabeling (Hoechst dye counterstained) at...
Ons of either 1 μg () or 5 μg () of ESO complexed with the NG-PEI2K(PEG550)copolymer. Muscles were h...
Ssion. TA muscles were given 10 twice-weekly intramuscular injections of 5 μg of ESO complexed with ...
EG550), or CG-PEI2K(PEG5K)copolymers, and harvested 3 wks after the first injection. Number of dystr...
EG550), or CG-PEI2K(PEG5K)copolymers, and harvested 3 wks after the first injection. Number of dystr...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-medi...
Duchenne muscular dystrophy (DMD) is a severe hereditary neuromuscular disorder caused by mutations ...
Abstract Duchenne muscular dystrophy (DMD) is a severe hereditary neuromuscular disorder caused by m...
Duchenne muscular dystrophy (DMD) is a genetic disease caused by a mutation in the X-linked Dytrophi...
Duchenne muscular dystrophy (DMD) is a severe hereditary neurodegenerative disorder due to mutations...
Mingxing Wang, Bo Wu, Jason D Tucker, Peijuan Lu, Qilong Lu Department of Neurology, McColl-Lockwoo...
AbstractThe use of antisense oligonucleotides (AOs) to induce exon skipping leading to generation of...