Bronchial epithelial spheroids: an alternative culture model to investigate epithelium inflammation-mediated COPD-4

<p><b>Copyright information:</b></p><p>Taken from "Bronchial epithelial spheroids: an alternative culture model to investigate epithelium inflammation-mediated COPD"</p><p>http://respiratory-research.com/content/8/1/86</p><p>Respiratory Research 2007;8(1):86-86.</p><p>Published online 26 Nov 2007</p><p>PMCID:PMC2214730.</p><p></p>n COPD and non-COPD BES. Results are expressed as pg of mediators per mg protein of BES. () Levels of IL-8, PGE2 and LTB4 after LPS stimulation (10 μg/ml LPS for 24 h). Results are expressed as fold increase by comparison to untreated conditions. () Correlations between LPS-induced IL-8, PGE2 and LTB4 fold-increase and postbronchodilator FEV. Results are obtained from 16 COPD smokers (filled rhombs) and 13 non-COPD smokers (open rhombs). Mann-Whitney U test for comparisons between groups. Correlations between variables were calculated by means of the Spearman's rank correlation test