miR-214 regulates HCC cell proliferation and apoptosis.

<p>(A) Relative cell number of HepG2 and SMMC-7721 cells at 48 hours post-transfection was evaluated using CCK-8 assay. (<b>B</b>) Cell growth rate of HepG2 and SMMC-7721 cells at 48 hours post-transfection was evaluated using Br-dU incorporation assay. (<b>C</b>) After 48 hours miR-214 mimics transfection, cells were labeled with Annexin V and analyzed by flow cytometry. (<b>D</b>) After 48 hours agomir-214 treatment, SMMC-7721 cells were labeled with Annexin V and analyzed by flow cytometry *P<0.05 vs untreated (HepG2 or SMMC-7721) or miR-con-treated.