<p>A) Representative pictures of the RNAi sensitive strain <i>nre-1 lin-15b</i> expressing <i>apl-1::gfp</i> on either control or <i>lrp-1</i> RNAi at the L4 stage. B) Fluorescence quantification of APL-1::GFP in the neuronal cell body. (n = 10–12) Experiments were performed twice. (**, P<0.01, ***, P<0.001) Error bars represent the s.e.m.</p
<p><b>A.</b> Western blots of GCPs isolated from newborn brain of wt and mutant mice. Blots were pro...
<p><b>A.</b> Cortical neurons from mouse embryos were plated onto poly-L-lysine-coated coverslips fo...
<p>Whole brains were collected at ZT0 and PDF was detected. Confocal stack images representing l-LNv...
<p>A) Representative pictures of APL-1::GFP expression in three head neurons of L4 worms grown for o...
and cholesterol metabolism. directly affects APL-1 levels as both lead to loss of APL-1::GFP fluore...
<p>(A, A’) Knockdown of LRP1 levels in U87 cells were measured by immunoblot. Tubulin served as a lo...
<p>A: RNA <i>in situ</i> hybridization at 3 hours after oligonucleotides injection. Injection of ApH...
<p>(A) Representative schematics and micrographs of NLG-1 GRASP fluorescence labeling PHB-AVA synaps...
<p>Primary cortical neurons cultured from C57Bl/6 mice were infected with lentivirus carrying LRP1-s...
<p><b>A)</b> The genetic background lacks <i>rde-1</i>, eliminating RNAi in all tissues. RDE-1 is se...
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition...
<p><i>Aplysia</i> sensory-to-motor neuron co-cultures were treated with 5×5-HT (10 µM, 5 minutes) an...
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition...
La-related protein 6 (LARP6) is an RNA binding protein with an intriguing set of functions and inter...
RNA interference (RNAi) is a potent mechanism that silences mRNA and protein expression in all cells...
<p><b>A.</b> Western blots of GCPs isolated from newborn brain of wt and mutant mice. Blots were pro...
<p><b>A.</b> Cortical neurons from mouse embryos were plated onto poly-L-lysine-coated coverslips fo...
<p>Whole brains were collected at ZT0 and PDF was detected. Confocal stack images representing l-LNv...
<p>A) Representative pictures of APL-1::GFP expression in three head neurons of L4 worms grown for o...
and cholesterol metabolism. directly affects APL-1 levels as both lead to loss of APL-1::GFP fluore...
<p>(A, A’) Knockdown of LRP1 levels in U87 cells were measured by immunoblot. Tubulin served as a lo...
<p>A: RNA <i>in situ</i> hybridization at 3 hours after oligonucleotides injection. Injection of ApH...
<p>(A) Representative schematics and micrographs of NLG-1 GRASP fluorescence labeling PHB-AVA synaps...
<p>Primary cortical neurons cultured from C57Bl/6 mice were infected with lentivirus carrying LRP1-s...
<p><b>A)</b> The genetic background lacks <i>rde-1</i>, eliminating RNAi in all tissues. RDE-1 is se...
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition...
<p><i>Aplysia</i> sensory-to-motor neuron co-cultures were treated with 5×5-HT (10 µM, 5 minutes) an...
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition...
La-related protein 6 (LARP6) is an RNA binding protein with an intriguing set of functions and inter...
RNA interference (RNAi) is a potent mechanism that silences mRNA and protein expression in all cells...
<p><b>A.</b> Western blots of GCPs isolated from newborn brain of wt and mutant mice. Blots were pro...
<p><b>A.</b> Cortical neurons from mouse embryos were plated onto poly-L-lysine-coated coverslips fo...
<p>Whole brains were collected at ZT0 and PDF was detected. Confocal stack images representing l-LNv...