Counter-regulated network signature in PLNs.

<p>A) Interactive Network of top 20 focus gene hubs. B) Ranked list of top 20 focus gene hubs on the basis of degree of connectivity. A merged network was generated from the top 7 networks of AAT treatment counter-regulated genes in PLNs. The Ingenuity pathways analysis (IPA) tool was used to generate and merge the significantly effected networks from the AAT treatment counter-regulated genes. The focus gene hubs were ranked in the merged network on the basis of degree of connectivity.