Ingenuity pathway analysis Network #1.

<p>Ingenuity pathway analysis was used to assemble a network based upon 22 differentially expressed focus genes that were upregulated in male VICs compared to female VICs. Genes are represented as nodes, with node shape representing the functional class of the gene product (seen in legend). Node color depicts degree of overrepresentation in male samples; uncolored nodes are depicted based upon evidence in the IPA Knowledge Base indicating a strong biological relevance to the network. *indicates multiple identifiers in the dataset file map to a single gene in the IPA Global Molecular Network. Corresponding fold change values are listed beneath each gene label. Focus gene names are defined in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0039980#pone.0039980.s005" target="_blank">Table S1</a>.