Enhanced resistance of LysM- PPARγ^KO mice to lethal infection with <i>Listeria monocytogenes</i>.

<p>(A) Survival of LysM- PPARγ^KO mice and LysM- PPARγ^WT littermates after intraperitoneal infection with 2×10⁴ (LD 50) 5×10⁵ (LD 80), 2×10⁶ (100× LD50) CFU of <i>Listeria</i>. (n = 10, one representative out of three experiments is shown ). LD 50: p = 0.04; LD 80; 0.01; 100× LD50: not significant difference. (B, C) Colony forming units of <i>Listeria monocytogenes</i> in liver (B) and spleen (C) of LysM- PPARγ^WT or LysM- PPARγ^KO mice infected i.p. with 2×10⁴ CFU. (n = 9); significance ** p = 0.005.