<p>The 10 GO-categories with the smallest (A) and the greatest (B) mean values of <i>rdnsv</i> are shown. The full list of all GO-categories with at least 1000 coding SNVs is given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038087#pone.0038087.s005" target="_blank">Table S3</a>. For each category the number of annotated genes, nonsynonymous and synonymous SNVs, the mean and standard deviation of individual <i>rdnsv</i> estimates across the 200 exomes, as well as the values of <i>rdnsv<sub>0</sub></i> and <i>rdnsv<sub>1</sub></i>, are shown.</p
<p>Gene ontology (GO) annotation of the assembled transcriptomes. <b>A:</b> The percentage distribut...
a<p>The number of genes mapped to each GO term in the whole MED transcriptome.</p>b<p>The number of ...
To measure the strength of natural selection that acts upon single nucleotide variants (SNVs) in a s...
<p>A) expression-based candidate genes and B) keyword-based candidate genes. The value of <i>rdnsv</...
<p>The label “Zeros” refers to the number of genes in the GO category with a divergence score of zer...
<p>Candidate genes for the nervous system (NSG) and the immune system (ISG) are defined by tissue sp...
<p>Cellular functions and metabolic activities are indicated by gene ontology (GO) categories that a...
<p>Numbers in parentheses are the total number of genes per comparison for each data-set or the GO r...
<p>Nervous system genes (NSG, light grey) show a smaller <i>rdnsv</i> than immune system genes (ISG,...
<p>Shown are the number of genes represented in each GO category. Raw and adjusted P-values are list...
<p>Significant gene categories for each cluster were identified using DAVID (Pearson correlation coe...
<p>12,503 unigenes were assigned to three GO categories containing 52 functional subcategories.</p
<p>Shown are pie charts presenting the relative abundance of the ten most frequently encountered gen...
a<p>Genes that have at least one SNP with a p-value < 0.05 and are involved in at least 4 gene sets ...
<p>Bars show the percent of sequences with a GO term annotation for each category.</p
<p>Gene ontology (GO) annotation of the assembled transcriptomes. <b>A:</b> The percentage distribut...
a<p>The number of genes mapped to each GO term in the whole MED transcriptome.</p>b<p>The number of ...
To measure the strength of natural selection that acts upon single nucleotide variants (SNVs) in a s...
<p>A) expression-based candidate genes and B) keyword-based candidate genes. The value of <i>rdnsv</...
<p>The label “Zeros” refers to the number of genes in the GO category with a divergence score of zer...
<p>Candidate genes for the nervous system (NSG) and the immune system (ISG) are defined by tissue sp...
<p>Cellular functions and metabolic activities are indicated by gene ontology (GO) categories that a...
<p>Numbers in parentheses are the total number of genes per comparison for each data-set or the GO r...
<p>Nervous system genes (NSG, light grey) show a smaller <i>rdnsv</i> than immune system genes (ISG,...
<p>Shown are the number of genes represented in each GO category. Raw and adjusted P-values are list...
<p>Significant gene categories for each cluster were identified using DAVID (Pearson correlation coe...
<p>12,503 unigenes were assigned to three GO categories containing 52 functional subcategories.</p
<p>Shown are pie charts presenting the relative abundance of the ten most frequently encountered gen...
a<p>Genes that have at least one SNP with a p-value < 0.05 and are involved in at least 4 gene sets ...
<p>Bars show the percent of sequences with a GO term annotation for each category.</p
<p>Gene ontology (GO) annotation of the assembled transcriptomes. <b>A:</b> The percentage distribut...
a<p>The number of genes mapped to each GO term in the whole MED transcriptome.</p>b<p>The number of ...
To measure the strength of natural selection that acts upon single nucleotide variants (SNVs) in a s...