Slopes and p-values for annual atrophy rates as a function of age shown in Figure 1.

<p>Bold underlined entries highlight slope values that significantly differ from zero. The three right hand columns give p-values for differences in slopes between cohorts. Two-sample t-test for independent samples with unequal variances (Satterthwaite’s method <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042325#pone.0042325-Rosner1" target="_blank">[37]</a>) was used to calculate p-values for pair-wise comparisons (last three columns).