Slopes and p-values for annual rates of clinical decline as a function of age shown in Figure 2.

<p>Bold underlined entries highlight slope values that significantly differ from zero. The three right hand columns give p-values for differences in slopes between cohorts. P-values for the last three columns were calculated as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042325#pone-0042325-t002" target="_blank">Table 2</a>.