Hepatic gene expression profile is altered in the wild type mice upon feeding an alcohol-containing liquid diet for 6 weeks.

<p><b>A.</b> IPA of the microarray data demonstrated dysregulation of genes involved in different pathways in the livers of mice fed alcohol diet. The number below each gene represents the fold change in expression (log2) in livers of mice fed alcoholic diet compared to that in controls. The shapes represent the functional class of each gene. <b>B.</b> qRT-PCR analysis validated microarray data of selected genes dysregulated in the wild type mice fed alcoholic diet compared to the controls. Fold changes in log10 scale are presented. qRT-PCR was performed with gene-specific primers using SYBR Green chemistry. Each sample was analyzed in quadruplicate.