Kaplan-Meier curve of breast cancer, glioblastoma (GBM) and ovarian cancer (OV) using network genes identified from cancer datasets.

<p>The p-values are computed using Log- rank test with 100 repeats. A: using Network 1 genes on NKI mixed cohort; B: using Van't Veer 70-gene signature <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002656#pcbi.1002656-VantVeer1" target="_blank">[1]</a> on NKI mixed cohort; C: using Network 1 genes on NKI LN+ cohort; D: using van't Veer 70-gene signature <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002656#pcbi.1002656-VantVeer1" target="_blank">[1]</a> on NKI LN+ cohort; E: using Network1 genes on NKI ER− cohort; F: using Van't Veer 70-gene signature on NKI ER− data. G: using Network 18 genes on TCGA GBM dataset; H: using 23-gene signature on TCGA GBM cohort <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002656#pcbi.1002656-Zhang3" target="_blank">[28]</a>. I: using Network 17 genes on TCGA OV cohort. J: using 19-gene signature on TCGA OV dataset <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002656#pcbi.1002656-Konstantinopoulos1" target="_blank">[34]</a>. Blue lines: good survival outcome group; Red lines: poor survival outcome group. LN+: lymph node positive. ER−: estrogen receptor negative.