The profile for the associations between the somatic mutations and survival time of patients with ovarian cancer.

<p>A (B): The Q-Q plot of the p-values from Log-rank test (Cox-PH regression) for the 562 considered MMSs. C: The volcano plot of the Cox-PH p-values and regression coefficients for the 562 considered MMSs. The horizontal dot line marks p = 0.05. D: The Venn diagram for the entire set of genes covered by the 22 selected MMSs. Specifically, the good (bad) genes are the genes involved in the GO terms corresponding to the 19 (3) positive (negative) MMSs which predict good (poor) clinical outcomes. A gene can belong to both the positive and negative MMSs, therefore may be double counted. E: The Venn diagram for the subset of the genes which are covered by the 22 selected MMSs. Each of the genes has the mutation burden in at least one training sample.