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Mapping peptide-region on the DBL4ε model and sequence alignment.

Sisse B. Ditlev (138366)
Morten A. Nielsen (88768)
Mafalda Resende (40847)
Mette Ø. Agerbæk (138367)
Vera V. Pinto (138368)
Pernille H. Andersen (138369)
Pamela Magistrado (103951)
John Lusingu (93673)
Madeleine Dahlbäck (40849)
Thor G. Theander (103961)
Ali Salanti (40851)

Publication date

September 2012

DOI

10.1371/journal.pone.0043663.g003

Abstract

<p>(A) Peptide-region P22–P26 mapped on a DBL4ε-FCR3 model. (B) FCR3 and 3D7 sequences aligned with 3 peptides produced for immunization.</p

Extracted data

Related items

(A): Amino-acid alignment (Fasta format) of the 20 clones sequenced after screening of the FliTrx random peptide display library against immobilized 9O12 IgG.

Julien Muzard (372727)
Laure Sarda-Mantel (372728)
Stéphane Loyau (134545)
Alain Meulemans (372729)
Liliane Louedec (134540)
Claudie Bantsimba-Malanda (372730)
Florence Hervatin (372731)
Joëlle Marchal-Somme (5653855)
Jean Baptiste Michel (372732)
Dominique Le Guludec (372733)
Philippe Billiald (372734)
Martine Jandrot-Perrus (372735)

February 2013

<p>The sequence of the peptide that has been selected for synthesis is underlined.</p

Conserved Binding Regions Provide the Clue for Peptide-Based Vaccine Development: A Chemical Perspective

Hernando Curtidor

December 2017

Synthetic peptides have become invaluable biomedical research and medicinal chemistry tools for stud...

Schematic localization of the identified spots along the α-T sequence and sequence alignment analysis.

Renata Curciarello (507903)
Paola L. Smaldini (507904)
Angela M. Candreva (507905)
Virginia González (507906)
Gustavo Parisi (464539)
Ana Cauerhff (507907)
Ivana Barrios (507908)
Luis Bruno Blanch (507909)
Carlos A. Fossati (297435)
Silvana Petruccelli (507910)
Guillermo H. Docena (431252)

January 2014

<p><b>A</b>) Analysis of the sequence alignment of α-T with IgE epitopes in bovine caseins (IEDB) sh...

Sequence alignment of peptides displayed on the surface of representative bR binding phage clones (a) and of nanodisc binding phage clones (b).

Marina Pavlidou (456435)
Karen Hänel (456436)
Luis Möckel (456437)
Dieter Willbold (111480)

September 2013

<p>Sequence alignment of peptides displayed on the surface of representative bR binding phage clones...

Defining Targets of Antibodies on DBL3X

Madeleine Dahlbäck (40849)
Thomas S Rask (40848)
Pernille H Andersen (274368)
Morten A Nielsen (40846)
Nicaise T Ndam (93411)
Mafalda Resende (40847)
Louise Turner (55117)
Philippe Deloron (87822)
Lars Hviid (75521)
Ole Lund (26628)
Anders Gorm Pedersen (241816)
Thor G Theander (55118)
Ali Salanti (40851)

February 2013

<p>Models of DBL3X in which the intensity of the gray and blue indicates reactivity of plasma tested...

Sequence alignment of 313–327 and 432–443 regions of several HCV strains/isolates.

Ruyu Liu (426164)
Huiying Rao (159262)
Jianghua Wang (159271)
Xingwang Xie (426165)
Dong Jiang (159266)
Xiaoben Pan (426166)
Ping Zhao (47228)
Henghui Zhang (159258)
Lai Wei (36699)

June 2013

<p>(A) Sequence alignment of region 313–327 from several HCV strains/isolates. (B) Sequence alignmen...

Mapping with functional mAbs identifies an epitope in domain D3.

Annalisa Nuccitelli (342679)
C. Daniela Rinaudo (120751)
Barbara Brogioni (427603)
Roberta Cozzi (120732)
Mario Ferrer-Navarro (427086)
Daniel Yero (427087)
John L. Telford (120748)
Guido Grandi (120744)
Xavier Daura (427091)
Martin Zacharias (9025)
Domenico Maione (120753)

June 2013

<p>(A) Mass spectrum obtained for the LysC digestion of BP-2a (upper panel) and peptides immunocaptu...

Relative Locations and Sequence Identities of Potential Vaccine Antigens

Will Fischer (243369)
H. X Liao (378134)
Barton F Haynes (272191)
Norman L Letvin (378135)
Bette Korber (18758)

February 2013

<p>The COT+ candidate vaccine sets represent one full-length COT protein plus numerous discrete sequ...

Helix-3 sequences.

Tamar Canello (198339)
Kati Frid (198343)
Ronen Gabizon (160721)
Silvia Lisa (195205)
Assaf Friedler (160766)
Jackob Moskovitz (177191)
María Gasset (195230)
Ruth Gabizon (198358)

February 2013

<p>(<b>A</b>) Helix-3 sequences in different PrP species. The 206–214 region, comprising M206 and M2...

The synthetic 8mer peptide sequences derived from a span of the immunodominant peptides Y1, Y2, Y3, and Y4 respectively.

Dongliang Liu (653854)
Yang Li (7082)
Jing Zhao (21160)
Fei Deng (170132)
Xiaomei Duan (653855)
Chun Kou (653856)
Ting Wu (106368)
Yijie Li (653857)
Yongxing Wang (653858)
Ji Ma (330962)
Jianhua Yang (653859)
Zhihong Hu (316172)
Fuchun Zhang (129371)
Yujiang Zhang (46399)
Surong Sun (653860)

November 2014

<p>The yellow and magenta highlighting represents the common sequences among peptides which react wi...

cDNA sequence and multiple sequence alignment of CFBD with other β-defensins.

Ping Meng (250328)
Shilong Yang (503374)
Chuanbin Shen (503375)
Ke Jiang (193253)
Mingqiang Rong (425750)
Ren Lai (50549)

December 2013

<p>(A) The cDNA sequence of CFBD. The amino acid of the precursor reading from the cDNA is suggested...

Amino acid sequence of hemagglutinin.

Rick A. Bright (43108)
Donald M. Carter (43109)
Corey J. Crevar (43110)
Franklin R. Toapanta (43111)
Jonathan D. Steckbeck (43112)
Kelly S. Cole (43113)
Niranjan M. Kumar (43114)
Peter Pushko (43115)
Gale Smith (43116)
Terrence M. Tumpey (43117)
Ted M. Ross (43118)

February 2013

<p>Top line represents the sequence for A/Indonesia/05/2005, which is the isolate used to generate v...

Conserved binding regions provide the clue for peptide-based vaccine development: A chemical perspective

Curtidor, Hernando
Reyes, César
Bermúdez, Adriana
Vanegas, Magnolia
Varela, Yahson
Patarrollo, Manuel Elkin

January 2017

Abstract: Synthetic peptides have become invaluable biomedical research and medicinal chemistry tool...

Localization of the selected peptides within the constant region of different antibody isotypes.

Luciano Polonelli (92344)
Tecla Ciociola (309997)
Walter Magliani (92353)
Pier Paolo Zanello (328939)
Tiziana D'Adda (328940)
Serena Galati (328941)
Flavia De Bernardis (264590)
Silvia Arancia (328942)
Elena Gabrielli (290619)
Eva Pericolini (290617)
Anna Vecchiarelli (290625)
Denise C. Arruda (320174)
Marcia R. Pinto (328943)
Luiz R. Travassos (92355)
Thelma A. Pertinhez (328944)
Alberto Spisni (328945)
Stefania Conti (92354)

February 2013

<p>Localization of the selected peptides within the constant region of different antibody isotypes.<...

Number of amino acids in the CDR3 region.

Sven Reiche (757119)
Yamen Dwai (757120)
Bianca M. Bussmann (757121)
Susanne Horn (231432)
Michael Sieg (757122)
Christian Jassoy (267172)

June 2015

<p>Percentages of BcR sequences of different lengths. <b>A</b>) Length distribution of heavy chain (...

(A): Amino-acid alignment (Fasta format) of the 20 clones sequenced after screening of the FliTrx random peptide display library against immobilized 9O12 IgG.

Julien Muzard (372727)
Laure Sarda-Mantel (372728)
Stéphane Loyau (134545)
Alain Meulemans (372729)
Liliane Louedec (134540)
Claudie Bantsimba-Malanda (372730)
Florence Hervatin (372731)
Joëlle Marchal-Somme (5653855)
Jean Baptiste Michel (372732)
Dominique Le Guludec (372733)
Philippe Billiald (372734)
Martine Jandrot-Perrus (372735)

February 2013

<p>The sequence of the peptide that has been selected for synthesis is underlined.</p

Conserved Binding Regions Provide the Clue for Peptide-Based Vaccine Development: A Chemical Perspective

Hernando Curtidor

December 2017

Synthetic peptides have become invaluable biomedical research and medicinal chemistry tools for stud...

Schematic localization of the identified spots along the α-T sequence and sequence alignment analysis.

Renata Curciarello (507903)
Paola L. Smaldini (507904)
Angela M. Candreva (507905)
Virginia González (507906)
Gustavo Parisi (464539)
Ana Cauerhff (507907)
Ivana Barrios (507908)
Luis Bruno Blanch (507909)
Carlos A. Fossati (297435)
Silvana Petruccelli (507910)
Guillermo H. Docena (431252)

January 2014

<p><b>A</b>) Analysis of the sequence alignment of α-T with IgE epitopes in bovine caseins (IEDB) sh...

Sequence alignment of peptides displayed on the surface of representative bR binding phage clones (a) and of nanodisc binding phage clones (b).

Marina Pavlidou (456435)
Karen Hänel (456436)
Luis Möckel (456437)
Dieter Willbold (111480)

September 2013

<p>Sequence alignment of peptides displayed on the surface of representative bR binding phage clones...

Defining Targets of Antibodies on DBL3X

Madeleine Dahlbäck (40849)
Thomas S Rask (40848)
Pernille H Andersen (274368)
Morten A Nielsen (40846)
Nicaise T Ndam (93411)
Mafalda Resende (40847)
Louise Turner (55117)
Philippe Deloron (87822)
Lars Hviid (75521)
Ole Lund (26628)
Anders Gorm Pedersen (241816)
Thor G Theander (55118)
Ali Salanti (40851)

February 2013

<p>Models of DBL3X in which the intensity of the gray and blue indicates reactivity of plasma tested...

Sequence alignment of 313–327 and 432–443 regions of several HCV strains/isolates.

Ruyu Liu (426164)
Huiying Rao (159262)
Jianghua Wang (159271)
Xingwang Xie (426165)
Dong Jiang (159266)
Xiaoben Pan (426166)
Ping Zhao (47228)
Henghui Zhang (159258)
Lai Wei (36699)

June 2013

<p>(A) Sequence alignment of region 313–327 from several HCV strains/isolates. (B) Sequence alignmen...

Mapping with functional mAbs identifies an epitope in domain D3.

Annalisa Nuccitelli (342679)
C. Daniela Rinaudo (120751)
Barbara Brogioni (427603)
Roberta Cozzi (120732)
Mario Ferrer-Navarro (427086)
Daniel Yero (427087)
John L. Telford (120748)
Guido Grandi (120744)
Xavier Daura (427091)
Martin Zacharias (9025)
Domenico Maione (120753)

June 2013

<p>(A) Mass spectrum obtained for the LysC digestion of BP-2a (upper panel) and peptides immunocaptu...

Relative Locations and Sequence Identities of Potential Vaccine Antigens

Will Fischer (243369)
H. X Liao (378134)
Barton F Haynes (272191)
Norman L Letvin (378135)
Bette Korber (18758)

February 2013

<p>The COT+ candidate vaccine sets represent one full-length COT protein plus numerous discrete sequ...

Helix-3 sequences.

Tamar Canello (198339)
Kati Frid (198343)
Ronen Gabizon (160721)
Silvia Lisa (195205)
Assaf Friedler (160766)
Jackob Moskovitz (177191)
María Gasset (195230)
Ruth Gabizon (198358)

February 2013

<p>(<b>A</b>) Helix-3 sequences in different PrP species. The 206–214 region, comprising M206 and M2...

The synthetic 8mer peptide sequences derived from a span of the immunodominant peptides Y1, Y2, Y3, and Y4 respectively.

Dongliang Liu (653854)
Yang Li (7082)
Jing Zhao (21160)
Fei Deng (170132)
Xiaomei Duan (653855)
Chun Kou (653856)
Ting Wu (106368)
Yijie Li (653857)
Yongxing Wang (653858)
Ji Ma (330962)
Jianhua Yang (653859)
Zhihong Hu (316172)
Fuchun Zhang (129371)
Yujiang Zhang (46399)
Surong Sun (653860)

November 2014

<p>The yellow and magenta highlighting represents the common sequences among peptides which react wi...

cDNA sequence and multiple sequence alignment of CFBD with other β-defensins.

Ping Meng (250328)
Shilong Yang (503374)
Chuanbin Shen (503375)
Ke Jiang (193253)
Mingqiang Rong (425750)
Ren Lai (50549)

December 2013

<p>(A) The cDNA sequence of CFBD. The amino acid of the precursor reading from the cDNA is suggested...

Amino acid sequence of hemagglutinin.

Rick A. Bright (43108)
Donald M. Carter (43109)
Corey J. Crevar (43110)
Franklin R. Toapanta (43111)
Jonathan D. Steckbeck (43112)
Kelly S. Cole (43113)
Niranjan M. Kumar (43114)
Peter Pushko (43115)
Gale Smith (43116)
Terrence M. Tumpey (43117)
Ted M. Ross (43118)

February 2013

<p>Top line represents the sequence for A/Indonesia/05/2005, which is the isolate used to generate v...

Conserved binding regions provide the clue for peptide-based vaccine development: A chemical perspective

Curtidor, Hernando
Reyes, César
Bermúdez, Adriana
Vanegas, Magnolia
Varela, Yahson
Patarrollo, Manuel Elkin

January 2017

Abstract: Synthetic peptides have become invaluable biomedical research and medicinal chemistry tool...

Localization of the selected peptides within the constant region of different antibody isotypes.

Luciano Polonelli (92344)
Tecla Ciociola (309997)
Walter Magliani (92353)
Pier Paolo Zanello (328939)
Tiziana D'Adda (328940)
Serena Galati (328941)
Flavia De Bernardis (264590)
Silvia Arancia (328942)
Elena Gabrielli (290619)
Eva Pericolini (290617)
Anna Vecchiarelli (290625)
Denise C. Arruda (320174)
Marcia R. Pinto (328943)
Luiz R. Travassos (92355)
Thelma A. Pertinhez (328944)
Alberto Spisni (328945)
Stefania Conti (92354)

February 2013

<p>Localization of the selected peptides within the constant region of different antibody isotypes.<...

Number of amino acids in the CDR3 region.

Sven Reiche (757119)
Yamen Dwai (757120)
Bianca M. Bussmann (757121)
Susanne Horn (231432)
Michael Sieg (757122)
Christian Jassoy (267172)

June 2015

<p>Percentages of BcR sequences of different lengths. <b>A</b>) Length distribution of heavy chain (...

(A): Amino-acid alignment (Fasta format) of the 20 clones sequenced after screening of the FliTrx random peptide display library against immobilized 9O12 IgG.

Julien Muzard (372727)
Laure Sarda-Mantel (372728)
Stéphane Loyau (134545)
Alain Meulemans (372729)
Liliane Louedec (134540)
Claudie Bantsimba-Malanda (372730)
Florence Hervatin (372731)
Joëlle Marchal-Somme (5653855)
Jean Baptiste Michel (372732)
Dominique Le Guludec (372733)
Philippe Billiald (372734)
Martine Jandrot-Perrus (372735)

February 2013

<p>The sequence of the peptide that has been selected for synthesis is underlined.</p

Conserved Binding Regions Provide the Clue for Peptide-Based Vaccine Development: A Chemical Perspective

Hernando Curtidor

December 2017

Synthetic peptides have become invaluable biomedical research and medicinal chemistry tools for stud...

Schematic localization of the identified spots along the α-T sequence and sequence alignment analysis.

Renata Curciarello (507903)
Paola L. Smaldini (507904)
Angela M. Candreva (507905)
Virginia González (507906)
Gustavo Parisi (464539)
Ana Cauerhff (507907)
Ivana Barrios (507908)
Luis Bruno Blanch (507909)
Carlos A. Fossati (297435)
Silvana Petruccelli (507910)
Guillermo H. Docena (431252)

January 2014

<p><b>A</b>) Analysis of the sequence alignment of α-T with IgE epitopes in bovine caseins (IEDB) sh...