Mice lacking RPMs exhibit wild type infection kinetics.

<p>(A) Parasitemia courses in 129Sv <i>SpiC^+/−</i> (<i>n</i> = 4) and <i>SpiC^−/−</i> (<i>n</i> = 5) mice are represented as geometric means with standard deviations and Mann-Whitney <i>p</i>-value. (B) Ly6c^lo monocyte (CD11b⁺ F4/80⁺ Ly6g⁻ SSC^lo Ly6c^lo) frequencies in blood and spleen of 129Sv <i>SpiC^+/−</i> (white bars) and <i>SpiC^−/−</i> mice (black bars) during the course of infection. Days depicted in blue and orange represent a 1.5-fold decrease or increase, respectively, in Ly6c^lo monocyte frequencies in blood and spleen of mice infected with <i>P. chabaudi</i>. (C) Ly6c^lo monocyte frequencies on day 12 post-infection. Means are presented with standard errors; <i>p</i>-values represent a two-tailed <i>t</i>-test assuming unequal variances. Data represent three independent experiments (<i>n</i> = 6–7 mice per group total).