CRB3 positive profiles in the outer plexiform layer of the adult mouse.

<p>Double immunofluorescence for CRB3 (green) and bassoon (red in <b>B–C</b>), synaptophysin (SYP, red in <b>E–F</b>), VGLUT1 (red in <b>H–I</b>) and β-catenin (red in <b>K–L</b>). <b>A–F</b>, CRB3 seems to surround the bassoon labeling (arrowheads in <b>A–C</b>) and colocalizes with SYP (arrowheads in <b>D–F</b>). <b>G–I</b>, VGLUT1 is present in the photoreceptors’ presynaptic terminals (<b>H–I</b>), where it colocalizes with CRB3 (arrowheads in <b>G–I</b>). <b>J–L</b>, β-catenin does not colocalize with CRB3 in the OPL (insets in <b>J–L</b>). Insets in J–L: Higher magnifications of the small squares. OPL, outer plexiform layer. Scale bars: 20 µm, 5 µm in inset.