<p><b>A</b>. Numbers of genes that meet fold cutoffs for activation/repression and statistical significance in response to unliganded TR expression in HepG2 cells, TRα and TRβ expressing cells were compared to parental. <b>B</b>. HeLa cells, TRα and TRβ expressing cells after doxycycline withdrawal to induce TRs versus doxycyclin treated cells. Similar results were obtained in comparisons with parental HeLa cells (not shown). <b>C</b>. Plots of fold induction/repression by TRβ (y-axis) versus TRα (x-axis) in HepG2 cells. <b>D</b>. Plots of fold induction/repression by TRβ (y-axis) versus TRα (x-axis) in HeLa cells.</p
<p>A, mRNA expression levels by RT-PCR of RKIP and 8 NRF2-inducible genes showing overexpression of ...
<p>Expression is shown for the genes (A) IL-1β, (B) IL-8, (C) IL-10, (D) TLR-3 and (E) TLR-9. Black ...
<p>All the controls tend to cluster together (left hand side) indicating a good normalization techni...
<p><b>A</b>. Numbers of genes that meet cutoffs for fold T<sub>3</sub> activation (upper panel, blue...
<p><b>A–D</b>. Numbers of genes that meet cut-offs for fold induction and statistical significance i...
<p><b>A</b>. Bar graph representing numbers of T<sub>3</sub> induced (upper panels) and repressed (l...
<p><b>A</b>. Equal expression of exogenously expressed TRs. Upper panel, western blot of extracts of...
<p>(A) Differential gene regulation in hADSC cells after TRα and TRβ KD. (B-G) Effects of TRα and TR...
<p>(A) Relative transgene (OA1) mRNA abundance in HeLa-OA1 and HepG2-OA1 cells cultured in full medi...
(A) Fold change versus expression strength for all detectable genes after 3 or 24 hours doxycycline ...
<p>A. Bar graph representing numbers of genes that display positive regulation (upper panel) or nega...
<p><b>A</b>. Representation of changes in all T<sub>3</sub>-dependent genes that meet cutoffs for fo...
<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052407#s3" target="_blank"...
<p>Heatmap depicting log2-transformed expression levels (left) and TRβ binding events within 1 KB, 5...
b) Graphical representation of expression levels of and following the drug treatment. Expressions of...
<p>A, mRNA expression levels by RT-PCR of RKIP and 8 NRF2-inducible genes showing overexpression of ...
<p>Expression is shown for the genes (A) IL-1β, (B) IL-8, (C) IL-10, (D) TLR-3 and (E) TLR-9. Black ...
<p>All the controls tend to cluster together (left hand side) indicating a good normalization techni...
<p><b>A</b>. Numbers of genes that meet cutoffs for fold T<sub>3</sub> activation (upper panel, blue...
<p><b>A–D</b>. Numbers of genes that meet cut-offs for fold induction and statistical significance i...
<p><b>A</b>. Bar graph representing numbers of T<sub>3</sub> induced (upper panels) and repressed (l...
<p><b>A</b>. Equal expression of exogenously expressed TRs. Upper panel, western blot of extracts of...
<p>(A) Differential gene regulation in hADSC cells after TRα and TRβ KD. (B-G) Effects of TRα and TR...
<p>(A) Relative transgene (OA1) mRNA abundance in HeLa-OA1 and HepG2-OA1 cells cultured in full medi...
(A) Fold change versus expression strength for all detectable genes after 3 or 24 hours doxycycline ...
<p>A. Bar graph representing numbers of genes that display positive regulation (upper panel) or nega...
<p><b>A</b>. Representation of changes in all T<sub>3</sub>-dependent genes that meet cutoffs for fo...
<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052407#s3" target="_blank"...
<p>Heatmap depicting log2-transformed expression levels (left) and TRβ binding events within 1 KB, 5...
b) Graphical representation of expression levels of and following the drug treatment. Expressions of...
<p>A, mRNA expression levels by RT-PCR of RKIP and 8 NRF2-inducible genes showing overexpression of ...
<p>Expression is shown for the genes (A) IL-1β, (B) IL-8, (C) IL-10, (D) TLR-3 and (E) TLR-9. Black ...
<p>All the controls tend to cluster together (left hand side) indicating a good normalization techni...