<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting phenylephrine and U46619-induced contraction responses to a 4 parameter logistic curve. Data were analyzed by 2 way ANOVA (sex x genotype) followed by Bonferonni post-hoc testing.</p>a<p><i>P</i><0.05, main gender effect.</p
<p>LTA application to WT mice increased contraction force at 10<sup>−7</sup> M phenylephrine. Result...
<p>(A) Concentration-response curve of endothelium-dependent relaxation to acetylcholine, with or wi...
<p>Maximal contraction to KCl (30 mM) (A). Maximal contraction to PGF2α (10μM) (B) and to PHE (1 μM)...
<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting p...
<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting v...
<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting v...
<p>Male (top) and female (bottom) aortic rings were contracted by the cumulative addition of phenyle...
<p>Male (top) and female (bottom) aortic rings were contracted submaximally by phenylephrine (a, c) ...
<p>Male (top) and female (bottom) aortic rings were contracted submaximally by phenylephrine (a, c) ...
Tissues were incubated for 30 min at 37°C in KPSS buffer at resting tensions of 500 mg after which t...
<p>Cumulative concentration-response curves to (A and D) acetylcholine (ACh), (B and E) ET-1 and (C ...
<p>PAR2-WT (a, b), PAR2-HET (c, d) and PAR2-KO (e, f) aortic rings were treated with 100 µM L-NAME a...
<p>Effect of pertussis toxin (PTx, 4 μM) and PD98,059 (1 μM) on the concentration-response curves to...
Tissues were incubated for 30 min at 37˚C in KPSS buffer at resting tensions of 500 mg after which t...
We characterized the thoracic aorta from the C57BL/6J mouse, a strain used commonly in the generatio...
<p>LTA application to WT mice increased contraction force at 10<sup>−7</sup> M phenylephrine. Result...
<p>(A) Concentration-response curve of endothelium-dependent relaxation to acetylcholine, with or wi...
<p>Maximal contraction to KCl (30 mM) (A). Maximal contraction to PGF2α (10μM) (B) and to PHE (1 μM)...
<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting p...
<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting v...
<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting v...
<p>Male (top) and female (bottom) aortic rings were contracted by the cumulative addition of phenyle...
<p>Male (top) and female (bottom) aortic rings were contracted submaximally by phenylephrine (a, c) ...
<p>Male (top) and female (bottom) aortic rings were contracted submaximally by phenylephrine (a, c) ...
Tissues were incubated for 30 min at 37°C in KPSS buffer at resting tensions of 500 mg after which t...
<p>Cumulative concentration-response curves to (A and D) acetylcholine (ACh), (B and E) ET-1 and (C ...
<p>PAR2-WT (a, b), PAR2-HET (c, d) and PAR2-KO (e, f) aortic rings were treated with 100 µM L-NAME a...
<p>Effect of pertussis toxin (PTx, 4 μM) and PD98,059 (1 μM) on the concentration-response curves to...
Tissues were incubated for 30 min at 37˚C in KPSS buffer at resting tensions of 500 mg after which t...
We characterized the thoracic aorta from the C57BL/6J mouse, a strain used commonly in the generatio...
<p>LTA application to WT mice increased contraction force at 10<sup>−7</sup> M phenylephrine. Result...
<p>(A) Concentration-response curve of endothelium-dependent relaxation to acetylcholine, with or wi...
<p>Maximal contraction to KCl (30 mM) (A). Maximal contraction to PGF2α (10μM) (B) and to PHE (1 μM)...