<p>Cumulative concentration-response curves to (A and D) acetylcholine (ACh), (B and E) ET-1 and (C and F) Phe. Relaxations are percent decrease in tension during contractions to phenylephrine. Contractions are percent reduction in lumen. (A to C) Aortic segments and (D–F) mesenteric artery in response to ACh, ET-1 and Phe in TET-1mice and NTg littermates. Results are Means±SEM, N = 8–10. *P<0.05.</p
<p>A. Representative recordings of changes in the [Ca<sup>2+</sup>]<sub>i</sub>, expressed as the ra...
<p>Maximal contraction to KCl (30 mM) (A). Maximal contraction to PGF2α (10μM) (B) and to PHE (1 μM)...
<p>Concentration-response curves and sensitivity (pEC<sub>50</sub>) to phenylephrine (PE) in endothe...
We characterized the thoracic aorta from the C57BL/6J mouse, a strain used commonly in the generatio...
<p>▴<b>) of L-NAME.</b> Relaxation responses are expressed as a percentage increase in lumen diamete...
<p>Relaxation responses are expressed as a percentage increase in lumen diameter after norepinephrin...
<p>Relaxation response curves to ACh (A–C) in aortic rings with endothelium precontracted with U-466...
<p>Baseline (at 5 mmHg) artery dimensions: outer diameter (OD), inner diameter (ID) and wall thickne...
<p>(A) Concentration-response curve of endothelium-dependent relaxation to acetylcholine, with or wi...
A. Phenylephrine (PE)-mediated vascular contraction in aortic rings from SED and EX mice was express...
<p>Concentration-response curves to acetylcholine (ACh, 0.001–3 µmol/l) were analysed at 4 (panel <b...
These studies examined adrenergic reactivity of mesenteric arteries and veins from deoxycorticostero...
<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting v...
<p>Concentration-response curves and sensitivity (pEC<sub>50</sub>) to acetylcholine (ACh) in endoth...
<p>A. The effect of acetylcholine on DAF-2 DA fluorescence intensity in mesenteric arteries from WT ...
<p>A. Representative recordings of changes in the [Ca<sup>2+</sup>]<sub>i</sub>, expressed as the ra...
<p>Maximal contraction to KCl (30 mM) (A). Maximal contraction to PGF2α (10μM) (B) and to PHE (1 μM)...
<p>Concentration-response curves and sensitivity (pEC<sub>50</sub>) to phenylephrine (PE) in endothe...
We characterized the thoracic aorta from the C57BL/6J mouse, a strain used commonly in the generatio...
<p>▴<b>) of L-NAME.</b> Relaxation responses are expressed as a percentage increase in lumen diamete...
<p>Relaxation responses are expressed as a percentage increase in lumen diameter after norepinephrin...
<p>Relaxation response curves to ACh (A–C) in aortic rings with endothelium precontracted with U-466...
<p>Baseline (at 5 mmHg) artery dimensions: outer diameter (OD), inner diameter (ID) and wall thickne...
<p>(A) Concentration-response curve of endothelium-dependent relaxation to acetylcholine, with or wi...
A. Phenylephrine (PE)-mediated vascular contraction in aortic rings from SED and EX mice was express...
<p>Concentration-response curves to acetylcholine (ACh, 0.001–3 µmol/l) were analysed at 4 (panel <b...
These studies examined adrenergic reactivity of mesenteric arteries and veins from deoxycorticostero...
<p>Values are means ± S.E.M., n = number of mice/group. Variables were determined by curve fitting v...
<p>Concentration-response curves and sensitivity (pEC<sub>50</sub>) to acetylcholine (ACh) in endoth...
<p>A. The effect of acetylcholine on DAF-2 DA fluorescence intensity in mesenteric arteries from WT ...
<p>A. Representative recordings of changes in the [Ca<sup>2+</sup>]<sub>i</sub>, expressed as the ra...
<p>Maximal contraction to KCl (30 mM) (A). Maximal contraction to PGF2α (10μM) (B) and to PHE (1 μM)...
<p>Concentration-response curves and sensitivity (pEC<sub>50</sub>) to phenylephrine (PE) in endothe...