Representative histological photomicrographs of liver of sham animals receiving vehicle (A), sham animals receiving tropisetron (B), trauma-hemorrhage animals receiving vehicle (C), trauma-hemorrhage animals receiving tropisetron (D), trauma-hemorrhage animals receiving tropisetron and SB-203580 (E), trauma-hemorrhage animals receiving SB-203580, (F), trauma-hemorrhage animals receiving tropisetron and chromium-mesoporphyrin (G), and trauma-hemorrhage animals receiving chromium-mesoporphyrin (H).

<p>Animals were killed 24 h after sham operation or trauma-hemorrhage with resuscitation. Liver were removed and processed as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0053203#s2" target="_blank">Methods</a>. Liver sections were stained with hematoxylin-eosin, examined at an original magnification X200, and photographed.