Histological liver necrosis after pair-feeding with ethanol (EtOH) or control (ctrl) chow 2 h after resuscitation.

<p>Sham operated animals underwent the same surgical procedures but hemorrhagic shock with resuscitation (H/R) was not carried out. Representative hematoxylin and eosin stained liver lobes from vehicle (veh) or D-JNKI-1-treated mice are shown (Fig 3A: ctrl-fed veh-treated mice, Fig 3B: ctrl-fed D-JNKI-1-treated mice, Fig 3C: EtOH-fed veh-treated mice, Fig 3D: EtOH-fed D-JNKI-1-treated mice after sham operation; Fig 3E: ctrl-fed veh-treated mice, Fig 3F: ctrl-fed D-JNKI-1-treated mice, Fig 3G: EtOH-fed veh-treated mice, Fig 3H: EtOH-fed D-JNKI-1-treated mice after H/R). Bar is 200 μm.