Tracking of X-Sight-labeled MSCs in control and chagasic mice 2 or 15 days after cell transplantation.

<p>The cells were intravenously injected (tail vein) in control and chagasic animals 1 month after infection for tracking by IVIS. (<b>A</b>) Representative images showing the distribution of transplanted MSCs viewed from in the ventral surface of the body. (<b>B</b>) Images of <i>ex vivo</i> organs showing the distribution of labeled MSCs. Note the majority of the signal is localized in the lung, liver and spleen of the animals. (<b>C–H</b>) Quantification of fluorescence intensity of <i>ex vivo</i> organs shown in images (B). The evaluated organs were (<b>C</b>) heart, (<b>D</b>) bladder, (<b>E</b>) lung, (<b>F</b>) liver, (<b>G</b>) spleen and (<b>H</b>) kidney. <i>P</i><0.05.