Cytokine profiles of mice immunized with coated SmRho-chitosan nanoparticles.

<p>Splenocytes isolated from mice immunized with CH-Rho-Alg, CH-Rho-Cpg-Alg, and CH-Rho-Alg (i.m.) were assayed for IL-10 (A) and INF-γ (B) production in response to <i>in vitro</i> stimulation with SWAP (25 µg/ml), rSmRho (25 µg/ml), SEA (25 µg/ml) or medium alone as control. <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0001894#s3" target="_blank">Results</a> represent the mean ± SD of each group. *Statistically significant differences between cytokines produced after SWAP, rSmRho or SEA stimulation compared with unstimulated splenocytes (control) (p<0.05).