<p>Percentages were calculated from the total number of mice analyzed; – indicates no tumors of that type; F = female, M = male.</p
<div><p>(A) Average number of carcinomas per mouse is plotted against the number of weeks postinitia...
<p>(<b>A</b>) Distribution of tumor grades (II–IV) in PDGF-B+X (P+X) and PDGF-B+HRG (P+H) injected <...
The p53 inhibitor murine double-minute gene 2 (Mdm2) is a target for potential cancer therapies, how...
<p>Kaplan-Meier survival curves of the indicated genotype of mice. The numbers of mice in each group...
<p>A majority of tumors forming in the mice were fixed and classified by morphology after sectioning...
<p>Kaplan-Meier survival curves of the indicated genotype of mice. The numbers of mice in each group...
<p>Kaplan-Meier survival curves of the indicated genotype of mice. The numbers of mice in each group...
Inactivation of the Arf-Mdm2-p53 tumor suppressor pathway is a necessary event for tumorigenesis. Ar...
<p>*, p<0.0025 by Fisher's Exact Test between control (<i>NIAM<sup>+/+</sup></i> and <i>NIAM<sup>+/m...
<p>(A) Kaplan-Meir tumor free survival curve for <i>Rnf8<sup>−/−</sup>p53<sup>+/−</sup></i> mice and...
Inactivation of the Arf-Mdm2-p53 tumor suppressor pathway is a necessary event for tumorigenesis. Ar...
<div><p>(A) Average number of papillomas (more than 2 mm in diameter) per mouse is plotted against t...
<p>A) Kaplan-Meier curve displaying tumor free survival of p53<sup>fl/fl</sup> and p53<sup>R172H</su...
<p>“Tumor incidence” indicates the average incidence of tumors in each mice (6 mice in each group, 6...
<p>The numbers of mice in each group are denoted by the <i>n</i> values. P value calculated by log-r...
<div><p>(A) Average number of carcinomas per mouse is plotted against the number of weeks postinitia...
<p>(<b>A</b>) Distribution of tumor grades (II–IV) in PDGF-B+X (P+X) and PDGF-B+HRG (P+H) injected <...
The p53 inhibitor murine double-minute gene 2 (Mdm2) is a target for potential cancer therapies, how...
<p>Kaplan-Meier survival curves of the indicated genotype of mice. The numbers of mice in each group...
<p>A majority of tumors forming in the mice were fixed and classified by morphology after sectioning...
<p>Kaplan-Meier survival curves of the indicated genotype of mice. The numbers of mice in each group...
<p>Kaplan-Meier survival curves of the indicated genotype of mice. The numbers of mice in each group...
Inactivation of the Arf-Mdm2-p53 tumor suppressor pathway is a necessary event for tumorigenesis. Ar...
<p>*, p<0.0025 by Fisher's Exact Test between control (<i>NIAM<sup>+/+</sup></i> and <i>NIAM<sup>+/m...
<p>(A) Kaplan-Meir tumor free survival curve for <i>Rnf8<sup>−/−</sup>p53<sup>+/−</sup></i> mice and...
Inactivation of the Arf-Mdm2-p53 tumor suppressor pathway is a necessary event for tumorigenesis. Ar...
<div><p>(A) Average number of papillomas (more than 2 mm in diameter) per mouse is plotted against t...
<p>A) Kaplan-Meier curve displaying tumor free survival of p53<sup>fl/fl</sup> and p53<sup>R172H</su...
<p>“Tumor incidence” indicates the average incidence of tumors in each mice (6 mice in each group, 6...
<p>The numbers of mice in each group are denoted by the <i>n</i> values. P value calculated by log-r...
<div><p>(A) Average number of carcinomas per mouse is plotted against the number of weeks postinitia...
<p>(<b>A</b>) Distribution of tumor grades (II–IV) in PDGF-B+X (P+X) and PDGF-B+HRG (P+H) injected <...
The p53 inhibitor murine double-minute gene 2 (Mdm2) is a target for potential cancer therapies, how...
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