<p>The protein levels and phosphorylation of PLIN1a in epididymal adipose tissue from fed mice and following a 12 h fast (<b>A, B</b>). The expression of PLIN1a was quantified relative to actin. Phosphorylation of PLIN1a was determined using an antibody to phosphorylated PKA-substrate (RRxS/T). (<b>C, D</b>) The protein level of PLIN1a was compared between tissue (Ti) and explants of the same tissue following <i>ex vivo</i> culture for 4 h (Ex). Adipose tissue was analysed from mice maintained on a Control or high fat (HFD) diet for 12 weeks. The expression of PLIN1a in explants was quantified relative to tissue (mean ± sem, n = 3). *p<0.05, ***p<0.001.</p
<div><p>Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride stor...
<p>(A) Comparison of lipid metabolism-related proteins. Whole lysates obtained from WT and <i>PRIP</...
The steep rise in both childhood and adult obesity over the past three decades has moved to the fore...
<p>Adipose tissue isolated from Plin1-/- and Plin+/+ mice was utilized for the following examination...
<p>The SVC cells isolated from adipose tissues in Plin1+/+, Plin1+/-, and Plin1-/- mice were differe...
<p>(A) Effect of Plin1 gene dosage on adipocyte differentiation. SVCs were isolated from epididymal ...
<p>(A) Representative confocal Plin2 immunofluorescence (green) images of liver sections from fasted...
<p><i>A</i>: Epididymal white adipose tissue immunoblots of insulin signaling components in chow- an...
<p>a. STAT1 binding to the PGC1α promoter was performed by ChIP assays from fed or fasted <i>STAT1</...
<p>Wild-type and IVA-PLA<sub>2</sub>-knockout (KO) mice were fed normal or high-fat (HF) diets for 8...
Obesity is a major risk factor for diabetes and heart disease. We previously reported that the inact...
<p>Cell homogenates from Plin2 overexpressing and control cells were probed with antibodies against ...
<p>Annexin V positive MPs from (A) ob control or ob/ob mice. Blood was collected by cardiac puncture...
The steep rise in both childhood and adult obesity over the past three decades has moved to the fore...
Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and ...
<div><p>Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride stor...
<p>(A) Comparison of lipid metabolism-related proteins. Whole lysates obtained from WT and <i>PRIP</...
The steep rise in both childhood and adult obesity over the past three decades has moved to the fore...
<p>Adipose tissue isolated from Plin1-/- and Plin+/+ mice was utilized for the following examination...
<p>The SVC cells isolated from adipose tissues in Plin1+/+, Plin1+/-, and Plin1-/- mice were differe...
<p>(A) Effect of Plin1 gene dosage on adipocyte differentiation. SVCs were isolated from epididymal ...
<p>(A) Representative confocal Plin2 immunofluorescence (green) images of liver sections from fasted...
<p><i>A</i>: Epididymal white adipose tissue immunoblots of insulin signaling components in chow- an...
<p>a. STAT1 binding to the PGC1α promoter was performed by ChIP assays from fed or fasted <i>STAT1</...
<p>Wild-type and IVA-PLA<sub>2</sub>-knockout (KO) mice were fed normal or high-fat (HF) diets for 8...
Obesity is a major risk factor for diabetes and heart disease. We previously reported that the inact...
<p>Cell homogenates from Plin2 overexpressing and control cells were probed with antibodies against ...
<p>Annexin V positive MPs from (A) ob control or ob/ob mice. Blood was collected by cardiac puncture...
The steep rise in both childhood and adult obesity over the past three decades has moved to the fore...
Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and ...
<div><p>Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride stor...
<p>(A) Comparison of lipid metabolism-related proteins. Whole lysates obtained from WT and <i>PRIP</...
The steep rise in both childhood and adult obesity over the past three decades has moved to the fore...