<p>Representative images and densitometric analyses of TLR3, TLR7, and TLR8 protein levels from 4 independent experiments for (A) the TLR3 agonist poly I:C, (B) the TLR7 agonist R837, and (C) the TLR7/8 agonist CLO97. Results are expressed as mean + SEM. *p<0.05 vs baseline.</p
<p>TLR6<sup>-</sup> or TLR6<sup>+</sup> trophoblast cells were treated with no treatment (NT) or PDG...
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal ...
<p>661W cells were either left untreated (control) or challenged with the indicated TLR ligands: Pam...
<p>Fold-increase and representative images and densitometric analyses of TLR3, TLR7, and TLR8 mRNA a...
<p>Measures of (A) urinary protein concentration, (B) maternal body weight, (C) spleen weight/body w...
<p>(A) Representative images where brown staining indicates immunoreactivity and blue indicates hema...
Toll-like receptors (TLRs) are an important part of the body's danger response system and crucial fo...
<p>P = pregnant, P+TLR3 = pregnant+TLR3 agonist poly I:C, P+TLR7 = pregnant+TLR7 agonist R837, P+TLR...
Toll-like receptors (TLRs) recognize conserved sequences on the surface of pathogens and trigger eff...
<p>Four TLR7/8 agonists were compared. (A) Structure of R848, (B) Structure of Hybrid-2, (C) Structu...
<p>Top: TLR7- and TLR8-agonistic activity. Reporter gene assays specific for human TLR7 and TLR8 wer...
<p>Measures of (A) systolic blood pressure, (B) aortic endothelium-dependent relaxation induced by a...
<p>(A) Seven TLR agonists were compared. (B) Representative structures of the TLR7/8 agonists used i...
<p>THP-1 cell treatment was described in <a href="http://www.plosone.org/article/info:doi/10.1371/jo...
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal ...
<p>TLR6<sup>-</sup> or TLR6<sup>+</sup> trophoblast cells were treated with no treatment (NT) or PDG...
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal ...
<p>661W cells were either left untreated (control) or challenged with the indicated TLR ligands: Pam...
<p>Fold-increase and representative images and densitometric analyses of TLR3, TLR7, and TLR8 mRNA a...
<p>Measures of (A) urinary protein concentration, (B) maternal body weight, (C) spleen weight/body w...
<p>(A) Representative images where brown staining indicates immunoreactivity and blue indicates hema...
Toll-like receptors (TLRs) are an important part of the body's danger response system and crucial fo...
<p>P = pregnant, P+TLR3 = pregnant+TLR3 agonist poly I:C, P+TLR7 = pregnant+TLR7 agonist R837, P+TLR...
Toll-like receptors (TLRs) recognize conserved sequences on the surface of pathogens and trigger eff...
<p>Four TLR7/8 agonists were compared. (A) Structure of R848, (B) Structure of Hybrid-2, (C) Structu...
<p>Top: TLR7- and TLR8-agonistic activity. Reporter gene assays specific for human TLR7 and TLR8 wer...
<p>Measures of (A) systolic blood pressure, (B) aortic endothelium-dependent relaxation induced by a...
<p>(A) Seven TLR agonists were compared. (B) Representative structures of the TLR7/8 agonists used i...
<p>THP-1 cell treatment was described in <a href="http://www.plosone.org/article/info:doi/10.1371/jo...
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal ...
<p>TLR6<sup>-</sup> or TLR6<sup>+</sup> trophoblast cells were treated with no treatment (NT) or PDG...
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal ...
<p>661W cells were either left untreated (control) or challenged with the indicated TLR ligands: Pam...