Ablation of proliferating cells in CNS decreases lifespan of SOD1<sup>G93A</sup> mice.
- Jean-Nicolas Audet (326107)
- Geneviève Gowing (326109)
- Renée Paradis (326111)
- Geneviève Soucy (5652298)
- Jean-Pierre Julien (84747)
Publication date
February 2013
DOIAbstract
<p>Kaplan-Meier survival curve shows that transgenic mice Sod1<sup>G93A</sup> (n = 7) treated with Ara-C between 75 and 115 days had a mean survival of 134 days while untreated SOD1<sup>G93A</sup> (n = 9) had a mean survival of 141 days. Log-rank test shows that this difference is significant (<i>p</i> = 0.0081).</p
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